Stephen Paul O'Brien - 29 Jan 2026 Form 4 Insider Report for Tvardi Therapeutics, Inc. (TVRD)

Role: Principal Accounting Officer
Signature: /s/ Dan Conn, Attorney-in-Fact
Issuer symbol: TVRD
Transactions as of: 29 Jan 2026
Net transactions value: $0
Form type: 4
Filing time: 02 Feb 2026, 16:30:16 UTC
Previous filing: 18 Dec 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
O'Brien Stephen Paul	Principal Accounting Officer	C/O TVARDI THERAPEUTICS, INC., 3 SUGAR CREEK CTR BLVD, STE 525, SUGAR LAND	/s/ Dan Conn, Attorney-in-Fact	02 Feb 2026	0002064889

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	TVRD	Employee Stock Option (right to buy)	Award	$0	+15,000		$0.000000	15,000	29 Jan 2026	Common Stock	15,000	$3.90	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The shares subject to the option shall vest and become exercisable in equal monthly installments over 48 months commencing on January 29, 2026, subject to the Reporting Person's continuous service through each applicable vesting date.