SEC ownership of PLUS THERAPEUTICS, INC.

Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001095981.

Comparable stake leader

HIGHBRIDGE CAPITAL MANAGEMENT LLC

Disclosed value leader

HIGHBRIDGE CAPITAL MANAGEMENT LLC

Comparable rows

26/38

Latest evidence

14 May 2026

Ownership snapshot CIK-linked ownership evidence from parsed SEC filings. 3 signals
Comparable ownership rows
26 of 38
Meaning: Rows with safely comparable ownership %
Latest 13D/G holder
HIGHBRIDGE CAPITAL MANAGEMENT LLC
Source: Latest parsed Schedule 13D/G stake
Latest parsed ownership date
14 May 2026
Freshness: Most recent filing date in this holder set
Issuer Names, identifiers, and filing context for this profile. 2 identity fields
Issuer CIK
0001095981
Issuer location
Austin, TX

Ownership snapshot

Top shareholders of PLUS THERAPEUTICS, INC. (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
HIGHBRIDGE CAPITAL MANAGE...
Disclosed value leader
HIGHBRIDGE CAPITAL MANAGE...
Comparable rows
26/38
Latest evidence
14 May 2026
13D/G 13F 3/4/5 Lead comparable stake: 7.1% 12 rows are not safely comparable across share classes. 13D/G row: HIGHBRIDGE CAPITAL MANAGEMENT LLC Showing 1-8 of 38 holder rows.

Quick read

HIGHBRIDGE CAPITAL MANAGEMENT LLC leads the comparable SEC ownership view at 7.1%.

26 of 38 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens HIGHBRIDGE CAPITAL MANAGEMENT LLC's linked filing trail.
Comparable ownership Top 5
HIGHBRIDGE CAPITAL MANAGEMENT LLC 7.1%
CVI Investments, Inc. 4.9%
Orin Hirschman 3.9%
S.H.N. Financial Investments Ltd. 1.5%
VANGUARD CAPITAL MANAGEMENT LLC 1.3%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-8 of 38 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
HIGHBRIDGE CAPITAL MANAGEMENT LLC
13D/G
7.1%
$2,105,263
13,157,894 shares
$0 31 Mar 2026
CVI Investments, Inc.
13D/G
4.9%
$1,441,596
9,009,978 shares
-$537,351 31 Mar 2026
Orin Hirschman
13D/G
3.9%
$410,778
1,283,681 shares
+$231,288 30 Jun 2025
S.H.N. Financial Investments Ltd.
13D/G
1.5%
$525,000
1,500,000 shares
+$101,586 14 Aug 2025
VANGUARD CAPITAL MANAGEMENT LLC
13F
Company
13F
1.3%
$395,617
2,427,098 shares
31 Mar 2026
GEODE CAPITAL MANAGEMENT, LLC
13F
Company
13F
1.1%
$327,979
2,016,314 shares
31 Mar 2026
BlackRock, Inc.
13F
Company
13F
0.97%
$288,838
1,776,372 shares
31 Mar 2026
VANGUARD FIDUCIARY TRUST CO
13F
Company
13F
0.63%
$189,695
1,163,776 shares
31 Mar 2026
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Forms 3/4/5 flow

Insider trading overview

Net insider flow leans to buying over the last 12 months. Net value: +$63,979.

Buys
$63,979
Insiders: 2
Sells
$0
Insiders: 0
Net
+$63,979
Shares: +130,000
Window
Last 12 months
4 rolling buckets
Buy value Sell value
Shares: 130,000 Shares: 0
Window (months) Buy shares Sell shares Buy value Sell value Net value
0-3 0 0 $0 $0 $0
3-6 0 0 $0 $0 $0
6-9 20,000 0 $10,200 $0 +$10,200
9-12 110,000 0 $53,779 $0 +$53,779

Reporting owners

Insider holders from Forms 3/4/5

Showing 1-11 of 11 reporting-owner rows connected to PLUS THERAPEUTICS, INC.. Open a relationship link for the CIK-to-CIK filing trail.

Rows
11
Largest Forms 3/4/5 holder
Marc H. Hedrick
Net 12M change
+$63,979
Latest report
14 May 2026
Name Relationship Holdings Value Past Year Net Change Change % Valuation Report Date
Marc H. Hedrick Chief Executive Officer, Director $359,173 Mixed 14 May 2026
Andrew John Hugh MacIntyre Sims Chief Financial Officer $89,095 +$10,200 +13% Mixed 14 May 2026
Robert P. Lenk Director $68,116 +$53,779 +375% Filing P/S 22 Aug 2025
Greg Petersen Director $66,043 Filing P/S 18 Feb 2025
Howard Clowes Director $35,405 Filing P/S 14 May 2026
Richard J. Hawkins Director $22,767 Filing P/S 14 May 2026
Kyle Guse Director $0 Mixed 14 May 2026
Ronald Asbury Andrews Director $0 Mixed 14 May 2026
Eric Joseph Daniels Chief Development Officer $0 Mixed 20 Apr 2026
An van Es-Johansson Director Mixed 14 May 2026
Norman D. LaFrance Chief Medical Officer Mixed 22 Feb 2024

Recent insider transactions for PLUS THERAPEUTICS, INC.

Showing up to 300 recent insider transactions from the last 12 months.

Insider Symbol Class Transaction % SEC-reported value SEC-reported price Shares Shares owned Date Ownership
An van Es-Johansson PSTV Stock Option (Right to Buy) Award 3,686 3,686 14 May 2026 Direct
An van Es-Johansson PSTV Restricted Stock Units Award 3,686 3,686 14 May 2026 Direct
Richard J. Hawkins PSTV Stock Option (Right to Buy) Award 3,686 3,686 14 May 2026 Direct
Richard J. Hawkins PSTV Restricted Stock Units Award 3,686 3,686 14 May 2026 Direct
Kyle Guse PSTV Stock Option (Right to Buy) Award 3,686 3,686 14 May 2026 Direct
Kyle Guse PSTV Restricted Stock Units Award 3,686 3,686 14 May 2026 Direct
Howard Clowes PSTV Stock Option (Right to Buy) Award 3,686 3,686 14 May 2026 Direct
Howard Clowes PSTV Restricted Stock Units Award 3,686 3,686 14 May 2026 Direct
Ronald Asbury Andrews PSTV Stock Option (Right to Buy) Award 5,286 3,686 14 May 2026 Direct
Ronald Asbury Andrews PSTV Restricted Stock Units Award 3,686 3,686 14 May 2026 Direct
Andrew John Hugh MacIntyre Sims PSTV Stock Option (Right to Buy) Award 3,443 3,443 14 May 2026 Direct
Andrew John Hugh MacIntyre Sims PSTV Restricted Stock Units Award 12.9% 3,443 30,055 14 May 2026 Direct
Marc H. Hedrick PSTV Stock Option (Right to Buy) Award 23,834 23,834 14 May 2026 Direct
Marc H. Hedrick PSTV Restricted Stock Units Award 16.3% 23,834 170,037 14 May 2026 Direct
Eric Joseph Daniels PSTV Stock Option (Right to Buy) Award 20,000 20,000 20 Apr 2026 Direct
Eric Joseph Daniels PSTV Restricted Stock Units Award 20,000 20,000 20 Apr 2026 Direct
Andrew John Hugh MacIntyre Sims PSTV Common Stock Options Exercise 63.4% 67,452 173,913 01 Apr 2026 Direct
Andrew John Hugh MacIntyre Sims PSTV Restricted Stock Units Options Exercise -9.21% -67,452 665,322 01 Apr 2026 Direct
Marc H. Hedrick PSTV Common Stock Options Exercise -22.3% -201,632 701,100 01 Apr 2026 Direct
Marc H. Hedrick PSTV Common Stock Options Exercise 47% 159,681 499,468 01 Apr 2026 Direct
Marc H. Hedrick PSTV Restricted Stock Units Options Exercise -9% -361,313 3,655,075 01 Apr 2026 Direct
Andrew John Hugh MacIntyre Sims PSTV Stock Option (Right to Buy) Award 349,541 349,541 25 Feb 2026 Direct
Andrew John Hugh MacIntyre Sims PSTV Restricted Stock Units Award 91.2% 349,542 732,774 25 Feb 2026 Direct
Marc H. Hedrick PSTV Stock Option (Right to Buy) Award 2,419,582 2,419,582 25 Feb 2026 Direct
Marc H. Hedrick PSTV Restricted Stock Units Award 151.5% 2,419,582 4,016,388 25 Feb 2026 Direct
Marc H. Hedrick PSTV Common Stock Options Exercise 88.7% 159,681 339,787 01 Jan 2026 Direct
Marc H. Hedrick PSTV Restricted Stock Units Options Exercise -9.09% -159,681 1,596,806 01 Jan 2026 Direct
Andrew John Hugh MacIntyre Sims PSTV Common Stock Options Exercise 56.2% 38,323 106,461 01 Jan 2026 Direct
Andrew John Hugh MacIntyre Sims PSTV Restricted Stock Units Options Exercise -9.09% -38,323 383,232 01 Jan 2026 Direct
Andrew John Hugh MacIntyre Sims PSTV Common Stock Purchase 41.6% $10,200 $0.5100 20,000 68,138 04 Nov 2025 Direct
Marc H. Hedrick PSTV Common Stock Options Exercise 781.8% 159,681 180,106 01 Oct 2025 Direct
Marc H. Hedrick PSTV Restricted Stock Units Options Exercise -8.33% -159,681 1,756,487 01 Oct 2025 Direct
Andrew John Hugh MacIntyre Sims PSTV Common Stock Options Exercise 390.4% 38,323 48,138 01 Oct 2025 Direct
Andrew John Hugh MacIntyre Sims PSTV Restricted Stock Units Options Exercise -8.33% -38,323 421,555 01 Oct 2025 Direct
Robert P. Lenk PSTV Common Stock Purchase 375.1% $53,779 $0.4889 110,000 139,327 22 Aug 2025 Direct
Marc H. Hedrick PSTV Restricted Stock Units Award 1,916,168 1,916,168 13 Aug 2025 Direct
Marc H. Hedrick PSTV Stock Option (Right to Buy) Award 5,748,506 5,748,506 13 Aug 2025 Direct
Andrew John Hugh MacIntyre Sims PSTV Restricted Stock Units Award 459,878 459,878 13 Aug 2025 Direct
Andrew John Hugh MacIntyre Sims PSTV Stock Option (Right to Buy) Award 1,379,636 1,379,636 13 Aug 2025 Direct
Kyle Guse PSTV Stock Option (Right to Buy) Award 337,794 297,794 13 Aug 2025 Direct
Richard J. Hawkins PSTV Stock Option (Right to Buy) Award 397,794 397,794 13 Aug 2025 Direct
Howard Clowes PSTV Stock Option (Right to Buy) Award 297,794 297,794 13 Aug 2025 Direct
Robert P. Lenk PSTV Stock Option (Right to Buy) Award 297,794 297,794 13 Aug 2025 Direct
An van Es-Johansson PSTV Stock Option (Right to Buy) Award 297,794 297,794 13 Aug 2025 Direct
* marks a reported price that did not pass the local price check.
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