| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 9.99% | 14.9M | 0 | 14.9M | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 6% | 8.9M | 0 | 8.9M | Kristin Mariani | Head of North America Compliance, CCO |