| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 9.99% | 3.38M | 0 | 3.38M | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 6.1% | 2.07M | 0 | 2.07M | Kristin Mariani | Head of North America Compliance, CCO |