| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 12% | 3,494,068 | 0 | 3,494,068 | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 11% | 2,959,525 | 0 | 2,959,525 | Kristin Mariani | Head of North America Compliance, CCO |