| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 11.1% | 3,684,383 | 0 | 3,684,383 | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 6.2% | 2,041,481 | 0 | 2,041,481 | Kristin Mariani | Head of North America Compliance, CCO |