| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 13.1% | 4.34M | 0 | 4.34M | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 7.6% | 2.5M | 0 | 2.5M | Kristin Mariani | Head of North America Compliance, CCO |