| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 5.6% | 2,080,367 | 0 | 2,080,367 | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 5% | 1,884,826 | 0 | 1,884,826 | Kristin Mariani | Head of North America Compliance, CCO |