| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 15.3% | 20,256,065 | 0 | 6,443,286 | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 5.6% | 7,384,314 | 0 | 7,384,314 | Kristin Mariani | Head of North America Compliance, CCO |