Point72 Asset Management, L.P. - 31 Dec 2025 SCHEDULE 13G/A Report for Praxis Precision Medicines, Inc. Common Stock, par value $0.0001 per share (PRAX)

Filing Manager: Point72 Asset Management, L.P.
Reporting Manager: Steven A. Cohen
Security: Praxis Precision Medicines, Inc. Common Stock, par value $0.0001 per share
Symbol: PRAX
Shares outstanding: 25,726,377 shares
Disclosed Ownership: 1,569,309 shares
Ownership: 6.1%
Form type: SCHEDULE 13G/A
Filing time: 17 Feb 2026, 16:31:06 UTC
Date of event: 31 Dec 2025
Previous filing: 14 Nov 2025
SEC: View on sec.gov

Reporting Managers (6)

Name	Ownership	Shares Owned	shared voting power	Signature	Title
Point72 Asset Management, L.P.	5.9%	1,503,376	1,503,376	/s/ Jason M. Colombo	Jason M. Colombo, Authorized Person
Point72 Capital Advisors, Inc.	5.9%	1,503,376	1,503,376	/s/ Jason M. Colombo	Jason M. Colombo, Authorized Person
Point72 Biotech Private Investments, LLC	0.3%	65,933	65,933	/s/ Vincent Tortorella	Vincent Tortorella, Authorized Person
Differentiated Ventures Investments, LLC	0.3%	65,933	65,933	/s/ Vincent Tortorella	Vincent Tortorella, Authorized Person
72 Investment Holdings, LLC	0.3%	65,933	65,933	/s/ Jason M. Colombo	Jason M. Colombo, Authorized Person
Steven A. Cohen	6.1%	1,569,309	1,569,309	/s/ Jason M. Colombo	Jason M. Colombo, Authorized Person