Point72 Asset Management, L.P. - Sep 30, 2025 SCHEDULE 13G/A Report for Praxis Precision Medicines, Inc. Common Stock, par value $0.0001 per share (PRAX)

Filing Manager: Point72 Asset Management, L.P.
Reporting Manager: Steven A. Cohen
Security: Praxis Precision Medicines, Inc. Common Stock, par value $0.0001 per share
Symbol: PRAX
Shares outstanding: 21.6M shares
Disclosed Ownership: 2.07M shares
Ownership: 9.6%
Form type: SCHEDULE 13G/A
Date filed: 11/14/2025, 04:00 PM
Date of event: Sep 30, 2025
Previous filing: Aug 14, 2025
SEC: View on sec.gov

Reporting Managers (6)

Name	Ownership	Shares Owned	shared voting power	Signature	Title
Point72 Asset Management, L.P.	9.3%	2.01M	2.01M	/s/ Jason M. Colombo	Jason M. Colombo, Authorized Person
Point72 Capital Advisors, Inc.	9.3%	2.01M	2.01M	/s/ Jason M. Colombo	Jason M. Colombo, Authorized Person
Point72 Biotech Private Investments, LLC	0.3%	65.9K	65.9K	/s/ Vincent Tortorella	Vincent Tortorella, Authorized Person
Differentiated Ventures Investments, LLC	0.3%	65.9K	65.9K	/s/ Vincent Tortorella	Vincent Tortorella, Authorized Person
72 Investment Holdings, LLC	0.3%	65.9K	65.9K	/s/ Jason M. Colombo	Jason M. Colombo, Authorized Person
Steven A. Cohen	9.6%	2.07M	2.07M	/s/ Jason M. Colombo	Jason M. Colombo, Authorized Person