Adage Capital Management, L.P. - 31 Dec 2025 SCHEDULE 13G/A Report for Karyopharm Therapeutics Inc. Common Stock, par value $0.0001 per share (KPTI)

Filing Manager
Adage Capital Management, L.P.
Reporting Manager
Adage Capital Management, L.P.
Security
Karyopharm Therapeutics Inc. Common Stock, par value $0.0001 per share
Symbol
KPTI
Shares outstanding
18,350,252 shares
Disclosed Ownership
436,736 shares
Ownership
2.4%
Form type
SCHEDULE 13G/A
Filing time
12 Feb 2026, 09:03:49 UTC
Date of event
31 Dec 2025
SEC
View on sec.gov

Reporting Managers (3)

Name Ownership Shares Owned sole voting power shared voting power Signature Title CIK
Adage Capital Management, L.P. 2.4% 436,736 0 436,736 /s/ Robert Atchinson By: Adage Capital Partners LLC, its General Partner, By: Robert Atchinson, its Managing Member
Robert Atchinson 2.4% 436,736 0 436,736 /s/ Robert Atchinson Robert Atchinson, individually
Phillip Gross 2.4% 436,736 0 436,736 /s/ Phillip Gross Phillip Gross, individually