Insider Trading & Ownership of Adage Capital Management, L.P.

Location
Boston, MA
Summary
The estimated value of insider holdings of Adage Capital Management, L.P. is at least $332,540,013 dollars as of 17 Oct 2025. Adage Capital Management, L.P. is the 10%+ Owner of Praxis Precision Medicines, Inc. and owns shares of Praxis Precision Medicines, Inc. (PRAX) stock worth about $288.42M. Adage Capital Management, L.P. is the 10%+ Owner of Solid Biosciences Inc. and owns shares of Solid Biosciences Inc. (SLDB) stock worth about $32.12M. Adage Capital Management, L.P. is the 10%+ Owner of ABEONA THERAPEUTICS INC. and owns shares of ABEONA THERAPEUTICS INC. (ABEO) stock worth about $12M.
Signature
/s/ Adage Capital Management, L.P.; By: its general partner Adage Capital Partners LLC; By its managing member Robert Atchinson
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Ownership of Adage Capital Management, L.P.

Symbol Company Relationship Holdings Value Past Year Net Change Change % Report Period
PRAX Praxis Precision Medicines, Inc. 10%+ Owner $288,424,500 +$33,198,124 +13% 16 Oct 2025
SLDB Solid Biosciences Inc. 10%+ Owner $32,115,515 18 Feb 2025
ABEO ABEONA THERAPEUTICS INC. 10%+ Owner $11,999,998 07 May 2024
EYPT EyePoint Pharmaceuticals, Inc. 10%+ Owner 18 Apr 2024

Insider Transactions Reported by Adage Capital Management, L.P.:

Sym Company Class Transaction % Value $ * Price $ Shares Shares After Date Ownership
* An asterisk sign (*) next to the price indicates that the price is likely invalid.