Javier B. Szwarcberg - 11 Dec 2025 Form 4 Insider Report for SPRUCE BIOSCIENCES, INC. (SPRB)

Source evidence Original filing metadata and source links for verification. 5 source fields
SEC form
4
Accepted by SEC
17 Dec 2025, 16:56:43 UTC
Prior SEC filing
12 Dec 2025
Next SEC filing
05 Jan 2026
Source filing
View source filing
Reporting owner 1 detail
Reporting owner signature
/s/ Samir Gharib, Attorney-in-Fact

Key filing fact

Javier B. Szwarcberg filed Form 4 for SPRUCE BIOSCIENCES, INC. (SPRB) on 17 Dec 2025.

Key facts

  • This page summarizes Javier B. Szwarcberg's Form 4 filing for SPRUCE BIOSCIENCES, INC. (SPRB).
  • 8 reported transactions and 4 derivative rows are listed below.
  • Accepted by SEC: 17 Dec 2025, 16:56.

Change

  • Previous filing in this sequence was filed on 12 Dec 2025.
  • Current net transaction value: -$109,711.

Research use

  • This tells you what this filing adds before you inspect full transaction and derivative tables.
  • You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001903669 Primary reporting owner

Szwarcberg Javier B.

Relationship
CHIEF EXECUTIVE OFFICER, Director
Address
C/O SPRUCE BIOSCIENCES, INC., 611 GATEWAY BOULEVARD, SUITE 740, SOUTH SAN FRANCISCO
Signature
/s/ Samir Gharib, Attorney-in-Fact
Signature date
17 Dec 2025

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

SPRB transaction

Common Stock

Options Exercise

Transaction value
$0
Shares
+1,480
Change %
+11%
Price
$0.000000
Shares after
14,478
Date
15 Dec 2025
Ownership
Direct
Footnotes
F1, F2
SPRB transaction

Common Stock

Tax liability

Transaction value
$60,664
Shares
-752
Change %
-5.2%
Price
$80.67
Shares after
13,726
Date
15 Dec 2025
Ownership
Direct
Footnotes
F1
SPRB transaction

Common Stock

Options Exercise

Transaction value
$0
Shares
+1,196
Change %
+8.7%
Price
$0.000000
Shares after
14,922
Date
15 Dec 2025
Ownership
Direct
Footnotes
F2, F3
SPRB transaction

Common Stock

Tax liability

Transaction value
$49,047
Shares
-608
Change %
-4.1%
Price
$80.67
Shares after
14,314
Date
15 Dec 2025
Ownership
Direct
Footnotes
F3

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

SPRB transaction Derivative

Employee Stock Option (right to buy)

Award

Transaction value
Shares
+1,666
Change %
Price
Shares after
1,666
Date
11 Dec 2025
Ownership
Direct
Underlying class
Common Stock
Underlying amount
1,666
Exercise price
$104.13
Footnotes
F4, F5, F6
SPRB transaction Derivative

Employee Stock Option (right to buy)

Disposed to Issuer

Transaction value
Shares
-1,666
Change %
-100%
Price
Shares after
0
Date
11 Dec 2025
Ownership
Direct
Underlying class
Common Stock
Underlying amount
1,666
Exercise price
$344.25
Footnotes
F4, F5, F6
SPRB transaction Derivative

Restricted Stock Units

Options Exercise

Transaction value
$0
Shares
-1,480
Change %
-50%
Price
$0.000000
Shares after
1,480
Date
15 Dec 2025
Ownership
Direct
Underlying class
Common Stock
Underlying amount
1,480
Exercise price
$0.000000
Footnotes
F1, F2
SPRB transaction Derivative

Restricted Stock Units

Options Exercise

Transaction value
$0
Shares
-1,196
Change %
-33%
Price
$0.000000
Shares after
2,392
Date
15 Dec 2025
Ownership
Direct
Underlying class
Common Stock
Underlying amount
1,196
Exercise price
$0.000000
Footnotes
F2, F3
* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 6 footnotes

Footnote F1

On December 5, 2022, the Reporting Person was granted 5,920 time-based restricted stock units ("RSUs"), subject to a 4-year vesting schedule, with 25% of the total number of RSUs vested on December 15, 2023 (the "Annual Vesting Date") and 25% of the total number of RSUs to vest in annual installments on each anniversary of the Annual Vesting Date thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2025, 1,480 RSUs vested, with 752 shares withheld for taxes, resulting in a net issuance of 728 shares.

Footnote F2

Each RSU represents a contingent right to receive one share of common stock of the Issuer.

Footnote F3

On December 14, 2023, the Reporting Person was granted a total of 9,658 RSUs. 50% or 4,784 of the total RSUs are performance-based and all vested on December 10, 2024. An addition of 50% or 4,784 of the total RSUs are time-based. 25% of which vested on December 15, 2024, and in equal annual installments thereafter, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). On December 15, 2025, 1,196 shares vested and 608 shares were withheld for taxes, resulting in a net issuance of 588 shares.

Footnote F4

The shares vest upon the achievement of specified performance goals, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan). 50% or 1,666 shares of the total shares vested on November 26, 2023. 50% or 1,666 shares of the total shares did not vest as the relevant performance goal was not achieved.

Footnote F5

The transactions reported herein reflect a one-time stock option repricing (the "Option Repricing") effective on December 11, 2025 (the "Repricing Date"). The Option Repricing applies to options with exercise prices of $106.09 per share or greater held by employees and directors of the Issuer who remained in continuous service with the Company as of the Repricing Date.

Footnote F6

Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $104.13 per share, the thirty (30)-day trailing volume-weighted average price of the Common Stock on the Nasdaq Capital Market on the Repricing Date. However, if an optionholder exercises a repriced option before the end of a retention period of one year (which period may be shorter in certain circumstances), such optionholder will be required to pay the original exercise price per share of such repriced option. No other changes were made to the repriced options in connection with the Option Repricing, including with respect to the vesting schedules, expiration dates or number of shares underlying such repriced options.

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