EcoR1 Capital, LLC - 02 May 2025 Form 4 Insider Report for PROTHENA CORP PUBLIC LTD CO (PRTA)

Reporting relationship: 10%+ Owner
Issuer ticker: PRTA
Reported as of: 02 May 2025
Net transaction value: -$50,839,807
SEC form: 4
Accepted by SEC: 06 May 2025, 19:06:05 UTC
Prior SEC filing: 18 Apr 2025
Next SEC filing: 13 May 2025
Source filing: View source filing
Reporting owner signature: /s/ Oleg Nodelman

Key filing fact

EcoR1 Capital, LLC filed Form 4 for PROTHENA CORP PUBLIC LTD CO (PRTA) on 06 May 2025.

Key facts

This page summarizes EcoR1 Capital, LLC's Form 4 filing for PROTHENA CORP PUBLIC LTD CO (PRTA).
3 reported transactions and 0 derivative rows are listed below.
Accepted by SEC: 06 May 2025, 19:06.

Change

Previous filing in this sequence was filed on 18 Apr 2025.
Current net transaction value: -$50,839,807.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001587114 Primary reporting owner

EcoR1 Capital, LLC

Relationship: 10%+ Owner
Address: 357 TEHAMA STREET #3, SAN FRANCISCO
Signature: /s/ Oleg Nodelman
Signature date: 06 May 2025

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

PRTA transaction

Ordinary Shares

Sale

Transaction value: $27,744,929
Shares: -3,317,938
Change %: -29%
Price: $8.36
Shares after: 8,266,342
Date: 02 May 2025
Ownership: See Note
Footnotes: F1, F2, F3, F4

PRTA transaction

Ordinary Shares

Sale

Transaction value: $7,930,166
Shares: -977,693
Change %: -12%
Price: $8.11
Shares after: 7,288,649
Date: 05 May 2025
Ownership: See Note
Footnotes: F1, F5, F6, F7

PRTA transaction

Ordinary Shares

Sale

Transaction value: $15,164,712
Shares: -1,984,053
Change %: -27%
Price: $7.64
Shares after: 5,304,596
Date: 06 May 2025
Ownership: See Note
Footnotes: F1, F8, F9, F10

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Section 16 status

EcoR1 Capital, LLC is no longer subject to Section 16 filing requirements. Form 4 or Form 5 obligations may still apply in specific circumstances.

Explanation of responses 10 footnotes

Footnote F1

The reporting persons are EcoR1 Capital, LLC ("Ecor1"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. ("Qualified Fund"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the "Fund"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself, Mr. Nodelman and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein.

Footnote F2

Qualified Fund sold 3,097,619 of the shares sold in this transaction.

Footnote F3

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $8.2715 to $9.1789, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission upon request, full information regarding the number of shares sold at each seperate price within the ranges set forth in this footnote and footnotes 6 and 9.

Footnote F4

After this transaction, Qualified Fund held 7,750,234 shares of the Issuer's Common Stock.

Footnote F5

Qualified Fund sold 916,492 of the shares of sold in this transaction.

Footnote F6

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $8.1097 to $8.1972, inclusive.

Footnote F7

After this transaction, Qualified Fund held 6,833,742 shares of the Issuer's Common Stock

Footnote F8

Qualified Fund sold 1,859,851 of the shares sold in this transaction.

Footnote F9

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $7.4637 to $8.5939, inclusive.

Footnote F10

After this transaction, Qualified Fund held 4,973,891 of the Issuer's Ordinary Shares.