Comparable stake leader
FMR LLC
Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001559053.
Comparable stake leader
FMR LLC
Disclosed value leader
FMR LLC
Comparable rows
50/50
Latest evidence
28 Jul 2026
Ownership snapshot
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Quick read
50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| FMR LLC |
13F
13D/G
Company
|
14%
from 13D/G
|
$70,480,344
7,199,218 shares
|
— | 30 Jun 2026 |
| William P. Scully |
13D/G
3/4/5
SCULLY WILLIAM P · 10%+ Owner
|
10%
|
$53,949,825
5,378,846 shares
|
+$972,910 | 07 May 2026 |
| Fennell Todd W. |
13D/G
|
9.8%
|
$46,300,217
5,010,846 shares
|
+$4,758,600 | 30 Jun 2026 |
| Rubric Capital Management LP |
13D/G
13F
Company
|
9.3%
|
$50,150,000
5,000,000 shares
|
+$13,266,370 | 31 Mar 2026 |
| BlackRock, Inc. |
13F
13D/G
Company
|
6.9%
from 13D/G
|
$47,657,280
4,867,955 shares
|
— | 30 Jun 2026 |
| ADAR1 Capital Management, LLC |
13F
13D/G
Company
|
2.7%
from 13D/G
|
$15,218,898
1,554,535 shares
|
— | 30 Jun 2026 |
| WELLINGTON MANAGEMENT GROUP LLP |
13D/G
|
0.2%
|
$821,299
108,208 shares
|
-$38,122,050 | 30 May 2025 |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
13D/G
Company · T. Rowe Price Associates, Inc.
|
0.1%
from 13D/G
|
$1,070,000
109,252 shares
|
— | 30 Jun 2026 |
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Forms 3/4/5 flow
Net insider flow leans to buying over the last 12 months. Net value: +$3,284,355.
| Window (months) | Buy shares | Sell shares | Buy value | Sell value | Net value |
|---|---|---|---|---|---|
| 0-3 | 382,500 | 16,048 | $3,420,330 | $135,975 | +$3,284,355 |
| 3-6 | 0 | 0 | $0 | $0 | $0 |
| 6-9 | 0 | 0 | $0 | $0 | $0 |
| 9-12 | 0 | 0 | $0 | $0 | $0 |
Reporting owners
Showing 1-20 of 27 reporting-owner rows connected to PROTHENA CORP PUBLIC LTD CO. Open a relationship link for the CIK-to-CIK filing trail.
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Valuation | Report Date |
|---|---|---|---|---|---|---|
| EcoR1 Capital, LLC | 10%+ Owner | $40,544,618 | Filing P/S | 02 May 2025 | ||
| William P. Scully | 10%+ Owner | $12,218,308 | +$3,420,330 | +39% | Mixed | 10 Aug 2026 |
| Gene G. Kinney | President and CEO, Director | $673,483 | Median | 28 Jul 2026 | ||
| Brandon S. Smith | Chief Operating Officer | $509,080 | Median | 28 Jul 2026 | ||
| Michael J. Malecek | Chief Legal Officer | $485,600 | Mixed | 03 Mar 2026 | ||
| Anne E. Kingston | Chief Strategy Officer | $472,635 | -$64,919 | -12% | Filing P/S | 28 Jul 2026 |
| Chad J. Swanson | Chief Development Officer | $398,776 | Median | 28 Jul 2026 | ||
| Tran B. Nguyen | Chief Strategy Officer and CFO | $393,606 | Median | 28 Jul 2026 | ||
| Wagner M. Zago | Chief Scientific Officer | $332,860 | Median | 28 Jul 2026 | ||
| Michael J. Isaacs | General Counsel & Company Sec. | $302,870 | -$71,055 | -19% | Filing P/S | 28 Jul 2026 |
| Karin L. Walker | Chief Accounting Officer | $97,900 | Median | 28 Jul 2026 | ||
| Lars G. Ekman | Director | Mixed | 15 May 2026 | |||
| Paula K. Cobb | Director | Mixed | 14 May 2025 | |||
| Carol D. Karp | Chief Regulatory Officer | Mixed | 05 Mar 2025 | |||
| William H. Dunn Jr. | Director | Mixed | 15 May 2026 | |||
| David A. Ford | Chief People Officer | Mixed | 05 Mar 2025 | |||
| Fennell Todd W. | 10%+ Owner | Mixed | 06 Aug 2026 | |||
| Daniel G. Welch | Director | Mixed | 15 May 2026 | |||
| Helen Susan Kim | Director | Mixed | 14 May 2025 | |||
| Shane Cooke | Director | Mixed | 15 May 2026 |
Showing up to 300 recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | SEC-reported value | SEC-reported price | Shares | Shares owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| William P. Scully | PRTA | Ordinary Shares, par value $0.01 per share | Gift | 31.8% | 251,553 | 1,041,553 | 10 Aug 2026 | Direct | ||
| William P. Scully | PRTA | Ordinary Shares, par value $0.01 per share | Purchase | 4.38% | $30,167 | $8.62 | 3,500 | 83,500 | 07 Aug 2026 | By Manatee Equity Fund LLC |
| William P. Scully | PRTA | Ordinary Shares, par value $0.01 per share | Purchase | 4.5% | $293,053 | $8.62 | 34,000 | 790,000 | 07 Aug 2026 | Direct |
| Anne E. Kingston | PRTA | Ordinary Shares, par value $0.01 per share | Sale | -12.1% | $64,919 | $8.47 | -7,662 | 55,782 | 29 Jul 2026 | Direct |
| Michael J. Isaacs | PRTA | Ordinary Shares, par value $0.01 per share | Sale | -19% | $71,055 | $8.47 | -8,386 | 35,745 | 29 Jul 2026 | Direct |
| Wagner M. Zago | PRTA | Ordinary Shares, par value $0.01 per share | Disposed to Issuer | -60% | -51,000 | 34,000 | 28 Jul 2026 | Direct | ||
| Wagner M. Zago | PRTA | Ordinary Shares, par value $0.01 per share | Options Exercise | 150% | 51,000 | 85,000 | 28 Jul 2026 | Direct | ||
| Wagner M. Zago | PRTA | Restricted Stock Units | Options Exercise | -100% | -51,000 | 0 | 28 Jul 2026 | Direct | ||
| Karin L. Walker | PRTA | Ordinary Shares, par value $0.01 per share | Disposed to Issuer | -60% | -15,000 | 10,000 | 28 Jul 2026 | Direct | ||
| Karin L. Walker | PRTA | Ordinary Shares, par value $0.01 per share | Options Exercise | 150% | 15,000 | 25,000 | 28 Jul 2026 | Direct | ||
| Karin L. Walker | PRTA | Restricted Stock Units | Options Exercise | -100% | -15,000 | 0 | 28 Jul 2026 | Direct | ||
| Chad J. Swanson | PRTA | Ordinary Shares, par value $0.01 per share | Tax liability | -7.84% | -3,467 | 40,733 | 28 Jul 2026 | Direct | ||
| Chad J. Swanson | PRTA | Ordinary Shares, par value $0.01 per share | Disposed to Issuer | -48% | -40,800 | 44,200 | 28 Jul 2026 | Direct | ||
| Chad J. Swanson | PRTA | Ordinary Shares, par value $0.01 per share | Options Exercise | 150% | 51,000 | 85,000 | 28 Jul 2026 | Direct | ||
| Chad J. Swanson | PRTA | Restricted Stock Units | Options Exercise | -100% | -51,000 | 0 | 28 Jul 2026 | Direct | ||
| Brandon S. Smith | PRTA | Ordinary Shares, par value $0.01 per share | Disposed to Issuer | -60% | -78,000 | 52,000 | 28 Jul 2026 | Direct | ||
| Brandon S. Smith | PRTA | Ordinary Shares, par value $0.01 per share | Options Exercise | 150% | 78,000 | 130,000 | 28 Jul 2026 | Direct | ||
| Brandon S. Smith | PRTA | Restricted Stock Units | Options Exercise | -100% | -78,000 | 0 | 28 Jul 2026 | Direct | ||
| Tran B. Nguyen | PRTA | Ordinary Shares, par value $0.01 per share | Disposed to Issuer | -58.6% | -57,000 | 40,205 | 28 Jul 2026 | Direct | ||
| Tran B. Nguyen | PRTA | Ordinary Shares, par value $0.01 per share | Options Exercise | 141.8% | 57,000 | 97,205 | 28 Jul 2026 | Direct | ||
| Tran B. Nguyen | PRTA | Restricted Stock Units | Options Exercise | -100% | -57,000 | 0 | 28 Jul 2026 | Direct | ||
| Gene G. Kinney | PRTA | Ordinary Shares, par value $0.01 per share | Disposed to Issuer | -55% | -84,000 | 68,793 | 28 Jul 2026 | Direct | ||
| Gene G. Kinney | PRTA | Ordinary Shares, par value $0.01 per share | Options Exercise | 122.1% | 84,000 | 152,793 | 28 Jul 2026 | Direct | ||
| Gene G. Kinney | PRTA | Restricted Stock Units | Options Exercise | -100% | -84,000 | 0 | 28 Jul 2026 | Direct | ||
| Anne E. Kingston | PRTA | Ordinary Shares, par value $0.01 per share | Tax liability | -5.23% | -3,498 | 63,444 | 28 Jul 2026 | Direct | ||
| Michael J. Isaacs | PRTA | Ordinary Shares, par value $0.01 per share | Tax liability | -9.61% | -4,694 | 44,131 | 28 Jul 2026 | Direct | ||
| William P. Scully | PRTA | Ordinary Shares, par value $0.01 per share | Purchase | 2.72% | $157,990 | $7.90 | 20,000 | 756,000 | 16 Jun 2026 | Direct |
| William P. Scully | PRTA | Ordinary Shares, par value $0.01 per share | Gift | -30.6% | -325,000 | 736,000 | 15 Jun 2026 | Direct | ||
| William P. Scully | PRTA | Ordinary Shares, par value $0.01 per share | Purchase | 13.4% | $1,021,225 | $8.17 | 125,000 | 1,061,000 | 11 Jun 2026 | Direct |
| William P. Scully | PRTA | Ordinary Shares, par value $0.01 per share | Purchase | 5.64% | $465,295 | $9.31 | 50,000 | 936,000 | 04 Jun 2026 | Direct |
| William P. Scully | PRTA | Ordinary Shares, par value $0.01 per share | Purchase | 5.98% | $471,300 | $9.43 | 50,000 | 886,000 | 02 Jun 2026 | Direct |
| William P. Scully | PRTA | Ordinary Shares, par value $0.01 per share | Purchase | 13.6% | $981,300 | $9.81 | 100,000 | 836,000 | 22 May 2026 | Direct |
| Daniel G. Welch | PRTA | Stock Option (Right to Buy) | Award | 27,000 | 27,000 | 15 May 2026 | Direct | |||
| Dennis J. Selkoe | PRTA | Stock Option (Right to Buy) | Award | 27,000 | 27,000 | 15 May 2026 | Direct | |||
| Lars G. Ekman | PRTA | Stock Option (Right to Buy) | Award | 27,000 | 27,000 | 15 May 2026 | Direct | |||
| William H. Dunn Jr. | PRTA | Stock Option (Right to Buy) | Award | 27,000 | 27,000 | 15 May 2026 | Direct | |||
| Shane Cooke | PRTA | Stock Option (Right to Buy) | Award | 27,000 | 27,000 | 15 May 2026 | Direct | |||
| Richard T. Collier | PRTA | Stock Option (Right to Buy) | Award | 27,000 | 27,000 | 15 May 2026 | Direct | |||
| Anne E. Kingston | PRTA | Stock Option (Right to Buy) | Award | 100,000 | 100,000 | 10 Apr 2026 | Direct | |||
| Wagner M. Zago | PRTA | Stock Option (Right to Buy) | Award | 190,000 | 190,000 | 03 Mar 2026 | Direct | |||
| Karin L. Walker | PRTA | Stock Option (Right to Buy) | Award | 150,000 | 150,000 | 03 Mar 2026 | Direct | |||
| Chad J. Swanson | PRTA | Stock Option (Right to Buy) | Award | 190,000 | 190,000 | 03 Mar 2026 | Direct | |||
| Brandon S. Smith | PRTA | Stock Option (Right to Buy) | Award | 190,000 | 190,000 | 03 Mar 2026 | Direct | |||
| Tran B. Nguyen | PRTA | Stock Option (Right to Buy) | Award | 230,000 | 230,000 | 03 Mar 2026 | Direct | |||
| Michael J. Malecek | PRTA | Stock Option (Right to Buy) | Award | 190,000 | 190,000 | 03 Mar 2026 | Direct | |||
| Gene G. Kinney | PRTA | Stock Option (Right to Buy) | Award | 520,000 | 520,000 | 03 Mar 2026 | Direct |