Key facts
- This page summarizes BAKER BROS. ADVISORS LP's Form 4 filing for BeOne Medicines Ltd. (ONC).
- 4 reported transactions and 12 derivative rows are listed below.
- Accepted by SEC: 16 Sep 2026, 16:18.
BAKER BROS. ADVISORS LP - 14 Sep 2026 Form 4 Insider Report for BeOne Medicines Ltd. (ONC)
- Reporting relationship
- Director
- Issuer ticker
- ONC
- Reported as of
- 14 Sep 2026
- Net transaction value
- $0
- SEC form
- 4
- Accepted by SEC
- 16 Sep 2026, 16:18:45 UTC
- Prior SEC filing
- 11 Aug 2026
- Next SEC filing
- 30 Sep 2026
- Source filing
- View source filing
- Reporting owner signature
- By: Baker Bros. Advisors LP, Name: Scott L. Lessing, Title: President /s/ Scott L. Lessing
Source evidence
Original filing metadata and source links for verification.
5 source fields
Reporting owner
1 detail
Key filing fact
BAKER BROS. ADVISORS LP filed Form 4 for BeOne Medicines Ltd. (ONC) on 16 Sep 2026.
Change
- Previous filing in this sequence was filed on 11 Aug 2026.
- Current net transaction value: $0.
Research use
- This tells you what this filing adds before you inspect full transaction and derivative tables.
- You can trace every row back to the original SEC filing document.
Evidence
Filed on Form 4
View source filing
Ownership activity is grounded in SEC Form 4 disclosures.
Reporting Owners (6)
CIK 0001263508
Primary reporting owner
BAKER BROS. ADVISORS LP
- Relationship
- Director
- Address
- 860 WASHINGTON STREET, 3RD FLOOR, NEW YORK
- Signature
- By: Baker Bros. Advisors LP, Name: Scott L. Lessing, Title: President /s/ Scott L. Lessing
- Signature date
- 16 Sep 2026
CIK 0001551139
667, L.P.
- Relationship
- Director
- Address
- 860 WASHINGTON STREET, 3RD FLOOR, NEW YORK
- Signature
- Baker Bros. Advisors LP, Mgmt. Co. and Inv. Adviser to 667, L.P., pursuant to authority granted by Baker Biotech Capital, L.P., GP to 667, L.P. Name: Scott L. Lessing, Title: President /s/ Scott L. Lessing
- Signature date
- 16 Sep 2026
CIK 0001580575
Baker Bros. Advisors (GP) LLC
- Relationship
- Director
- Address
- 860 WASHINGTON STREET, 3RD FLOOR, NEW YORK
- Signature
- By: Baker Bros. Advisors (GP) LLC, Name: Scott L. Lessing, Title: President /s/ Scott L. Lessing
- Signature date
- 16 Sep 2026
CIK 0001363364
Baker Brothers Life Sciences LP
- Relationship
- Director
- Address
- 860 WASHINGTON STREET, 3RD FLOOR, NEW YORK
- Signature
- Baker Bros. Advisors LP, Mgmt. Co. and Inv. Adviser to BAKER BROTHERS LIFE SCIENCES, L.P., pursuant to authority granted by Baker Brothers Life Sciences Capital, L.P., GP to Baker Brothers Life Sciences, L.P., /s/ Name: Scott L. Lessing, Title: President
- Signature date
- 16 Sep 2026
CIK 0001087940
BAKER FELIX
- Relationship
- Director
- Address
- 860 WASHINGTON STREET, 3RD FLOOR, NEW YORK
- Signature
- /s/ Felix J. Baker
- Signature date
- 16 Sep 2026
CIK 0001087939
BAKER JULIAN
- Relationship
- Director
- Address
- 860 WASHINGTON STREET, 3RD FLOOR, NEW YORK
- Signature
- /s/ Julian C. Baker
- Signature date
- 16 Sep 2026
Reported non-derivative transactions
Shares, units, or other non-derivative securities reported in this filing.
ONC
transaction
American Depositary Shares
Options Exercise
- Transaction value
- Shares
- +30,768
- Change %
- +4.2%
- Price
- $36.83*
- Shares after
- 761,410
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Footnotes
- F1, F2, F3, F4, F5, F6, F7, F8, F9, F14, F18
ONC
transaction
American Depositary Shares
Options Exercise
- Transaction value
- Shares
- +30,768
- Change %
- +4.2%
- Price
- $36.83*
- Shares after
- 761,410
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Footnotes
- F1, F2, F3, F4, F5, F6, F7, F8, F9, F14, F18
ONC
transaction
American Depositary Shares
Options Exercise
- Transaction value
- Shares
- +30,768
- Change %
- +4.2%
- Price
- $36.83*
- Shares after
- 761,410
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Footnotes
- F1, F2, F3, F4, F5, F6, F7, F8, F9, F14, F18
ONC
transaction
American Depositary Shares
Options Exercise
- Transaction value
- Shares
- +30,768
- Change %
- +4.2%
- Price
- $36.83*
- Shares after
- 761,410
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Footnotes
- F1, F2, F3, F4, F5, F6, F7, F8, F9, F14, F18
ONC
transaction
American Depositary Shares
Options Exercise
- Transaction value
- Shares
- +30,768
- Change %
- +4.2%
- Price
- $36.83*
- Shares after
- 761,410
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Footnotes
- F1, F2, F3, F4, F5, F6, F7, F8, F9, F14, F18
ONC
transaction
American Depositary Shares
Options Exercise
- Transaction value
- Shares
- +30,768
- Change %
- +4.2%
- Price
- $36.83*
- Shares after
- 761,410
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Footnotes
- F1, F2, F3, F4, F5, F6, F7, F8, F9, F14, F18
ONC
transaction
American Depositary Shares
Options Exercise
- Transaction value
- Shares
- +30,768
- Change %
- +0.38%
- Price
- $36.83*
- Shares after
- 8,099,179
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Footnotes
- F1, F2, F4, F5, F6, F7, F8, F9, F11, F14, F18
ONC
transaction
American Depositary Shares
Options Exercise
- Transaction value
- Shares
- +30,768
- Change %
- +0.38%
- Price
- $36.83*
- Shares after
- 8,099,179
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Footnotes
- F1, F2, F4, F5, F6, F7, F8, F9, F11, F14, F18
ONC
transaction
American Depositary Shares
Options Exercise
- Transaction value
- Shares
- +30,768
- Change %
- +0.38%
- Price
- $36.83*
- Shares after
- 8,099,179
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Footnotes
- F1, F2, F4, F5, F6, F7, F8, F9, F11, F14, F18
ONC
transaction
American Depositary Shares
Options Exercise
- Transaction value
- Shares
- +30,768
- Change %
- +0.38%
- Price
- $36.83*
- Shares after
- 8,099,179
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Footnotes
- F1, F2, F4, F5, F6, F7, F8, F9, F11, F14, F18
ONC
transaction
American Depositary Shares
Options Exercise
- Transaction value
- Shares
- +30,768
- Change %
- +0.38%
- Price
- $36.83*
- Shares after
- 8,099,179
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Footnotes
- F1, F2, F4, F5, F6, F7, F8, F9, F11, F14, F18
ONC
transaction
American Depositary Shares
Options Exercise
- Transaction value
- Shares
- +30,768
- Change %
- +0.38%
- Price
- $36.83*
- Shares after
- 8,099,179
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Footnotes
- F1, F2, F4, F5, F6, F7, F8, F9, F11, F14, F18
ONC
holding
American Depositary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 10,418
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F14, F15
ONC
holding
American Depositary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 10,418
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F14, F15
ONC
holding
American Depositary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 10,418
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F14, F15
ONC
holding
American Depositary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 10,418
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F14, F15
ONC
holding
American Depositary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 10,418
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F14, F15
ONC
holding
American Depositary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 10,418
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F14, F15
ONC
holding
American Depositary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 10,418
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F14, F16
ONC
holding
American Depositary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 10,418
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F14, F16
ONC
holding
American Depositary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 10,418
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F14, F16
ONC
holding
American Depositary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 10,418
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F14, F16
ONC
holding
American Depositary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 10,418
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F14, F16
ONC
holding
American Depositary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 10,418
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F14, F16
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 1
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F12
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 1
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F12
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 1
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F12
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 1
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F12
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 1
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F12
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 1
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F12
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 1
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F13
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 1
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F13
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 1
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F13
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 1
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F13
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 1
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F13
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 1
- Date
- 14 Sep 2026
- Ownership
- Direct
- Footnotes
- F13
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 161,546
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Footnotes
- F3, F4, F6, F7, F8, F9, F10
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 161,546
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Footnotes
- F3, F4, F6, F7, F8, F9, F10
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 161,546
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Footnotes
- F3, F4, F6, F7, F8, F9, F10
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 161,546
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Footnotes
- F3, F4, F6, F7, F8, F9, F10
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 161,546
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Footnotes
- F3, F4, F6, F7, F8, F9, F10
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 161,546
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Footnotes
- F3, F4, F6, F7, F8, F9, F10
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 161,550
- Date
- 14 Sep 2026
- Ownership
- See Footnote
- Footnotes
- F4, F6, F7, F8, F9, F10, F11
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 161,550
- Date
- 14 Sep 2026
- Ownership
- See Footnote
- Footnotes
- F4, F6, F7, F8, F9, F10, F11
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 161,550
- Date
- 14 Sep 2026
- Ownership
- See Footnote
- Footnotes
- F4, F6, F7, F8, F9, F10, F11
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 161,550
- Date
- 14 Sep 2026
- Ownership
- See Footnote
- Footnotes
- F4, F6, F7, F8, F9, F10, F11
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 161,550
- Date
- 14 Sep 2026
- Ownership
- See Footnote
- Footnotes
- F4, F6, F7, F8, F9, F10, F11
ONC
holding
Ordinary Shares
No transaction description listed
- Transaction value
- Shares
- Change %
- Price
- Shares after
- 161,550
- Date
- 14 Sep 2026
- Ownership
- See Footnote
- Footnotes
- F4, F6, F7, F8, F9, F10, F11
Reported derivative securities
Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.
ONC
transaction
Derivative
Non-Qualified Share Options
Options Exercise
- Transaction value
- Shares
- -30,768
- Change %
- -100%
- Price
- $0.000000*
- Shares after
- 0
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Underlying class
- American Depositary Shares
- Underlying amount
- 30,768
- Exercise price
- $36.83
- Footnotes
- F1, F2, F3, F4, F6, F7, F9, F17, F18
ONC
transaction
Derivative
Non-Qualified Share Options
Options Exercise
- Transaction value
- Shares
- -30,768
- Change %
- -100%
- Price
- $0.000000*
- Shares after
- 0
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Underlying class
- American Depositary Shares
- Underlying amount
- 30,768
- Exercise price
- $36.83
- Footnotes
- F1, F2, F3, F4, F6, F7, F9, F17, F18
ONC
transaction
Derivative
Non-Qualified Share Options
Options Exercise
- Transaction value
- Shares
- -30,768
- Change %
- -100%
- Price
- $0.000000*
- Shares after
- 0
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Underlying class
- American Depositary Shares
- Underlying amount
- 30,768
- Exercise price
- $36.83
- Footnotes
- F1, F2, F3, F4, F6, F7, F9, F17, F18
ONC
transaction
Derivative
Non-Qualified Share Options
Options Exercise
- Transaction value
- Shares
- -30,768
- Change %
- -100%
- Price
- $0.000000*
- Shares after
- 0
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Underlying class
- American Depositary Shares
- Underlying amount
- 30,768
- Exercise price
- $36.83
- Footnotes
- F1, F2, F3, F4, F6, F7, F9, F17, F18
ONC
transaction
Derivative
Non-Qualified Share Options
Options Exercise
- Transaction value
- Shares
- -30,768
- Change %
- -100%
- Price
- $0.000000*
- Shares after
- 0
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Underlying class
- American Depositary Shares
- Underlying amount
- 30,768
- Exercise price
- $36.83
- Footnotes
- F1, F2, F3, F4, F6, F7, F9, F17, F18
ONC
transaction
Derivative
Non-Qualified Share Options
Options Exercise
- Transaction value
- Shares
- -30,768
- Change %
- -100%
- Price
- $0.000000*
- Shares after
- 0
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Underlying class
- American Depositary Shares
- Underlying amount
- 30,768
- Exercise price
- $36.83
- Footnotes
- F1, F2, F3, F4, F6, F7, F9, F17, F18
ONC
transaction
Derivative
Non-Qualified Share Options
Options Exercise
- Transaction value
- Shares
- -30,768
- Change %
- -100%
- Price
- $0.000000*
- Shares after
- 0
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Underlying class
- American Depositary Shares
- Underlying amount
- 30,768
- Exercise price
- $36.83
- Footnotes
- F1, F2, F4, F6, F7, F9, F11, F17, F18
ONC
transaction
Derivative
Non-Qualified Share Options
Options Exercise
- Transaction value
- Shares
- -30,768
- Change %
- -100%
- Price
- $0.000000*
- Shares after
- 0
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Underlying class
- American Depositary Shares
- Underlying amount
- 30,768
- Exercise price
- $36.83
- Footnotes
- F1, F2, F4, F6, F7, F9, F11, F17, F18
ONC
transaction
Derivative
Non-Qualified Share Options
Options Exercise
- Transaction value
- Shares
- -30,768
- Change %
- -100%
- Price
- $0.000000*
- Shares after
- 0
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Underlying class
- American Depositary Shares
- Underlying amount
- 30,768
- Exercise price
- $36.83
- Footnotes
- F1, F2, F4, F6, F7, F9, F11, F17, F18
ONC
transaction
Derivative
Non-Qualified Share Options
Options Exercise
- Transaction value
- Shares
- -30,768
- Change %
- -100%
- Price
- $0.000000*
- Shares after
- 0
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Underlying class
- American Depositary Shares
- Underlying amount
- 30,768
- Exercise price
- $36.83
- Footnotes
- F1, F2, F4, F6, F7, F9, F11, F17, F18
ONC
transaction
Derivative
Non-Qualified Share Options
Options Exercise
- Transaction value
- Shares
- -30,768
- Change %
- -100%
- Price
- $0.000000*
- Shares after
- 0
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Underlying class
- American Depositary Shares
- Underlying amount
- 30,768
- Exercise price
- $36.83
- Footnotes
- F1, F2, F4, F6, F7, F9, F11, F17, F18
ONC
transaction
Derivative
Non-Qualified Share Options
Options Exercise
- Transaction value
- Shares
- -30,768
- Change %
- -100%
- Price
- $0.000000*
- Shares after
- 0
- Date
- 14 Sep 2026
- Ownership
- See Footnotes
- Underlying class
- American Depositary Shares
- Underlying amount
- 30,768
- Exercise price
- $36.83
- Footnotes
- F1, F2, F4, F6, F7, F9, F11, F17, F18
* marks a reported price that did not pass the local price check.
Additional SEC filing notes
Filing notes and footnotes
Explanation of responses 18 footnotes
Footnote F1
American Depositary Shares ("ADS") of BeOne Medicines Ltd. (the "Issuer") received upon exercise of 15,384 non-qualified share options to purchase ADS or Ordinary Shares ("Share Options") that were issued to each of Ranjeev Krishana and Michael Goller, full-time employees of Baker Bros. Advisors LP (the "Adviser") for their prior service as directors of the Issuer. Ranjeev Krishana and Michael Goller, pursuant to the policies of the Adviser, do not have any right to the pecuniary interest in the Share Options issued for their prior service on the board of directors of the Issuer (the "Board") or the ADS or Ordinary Shares received upon exercise of such Share Options.
Footnote F2
Each of 667, L.P. ("667") and Baker Brothers Life Sciences, L.P. ("Life Sciences", and together with 667, the "Funds") and their affiliates and control persons owns an indirect proportionate pecuniary interest in the ADS received upon exercise of the Share Options issued in connection with Ranjeev Krishana and Michael Goller's prior service on the Board less the exercise cost of those Share Options.
Footnote F3
After giving effect to the transaction reported herein and as a result of their ownership interest in (i) Baker Biotech Capital, L.P. and (ii) 667, Julian C. Baker and Felix J. Baker each may be deemed to have an indirect pecuniary interest in securities reported in column 5 of Table I and in column 9 of Table II directly held by or held for the benefit of 667, a limited partnership of which the sole general partner is Baker Biotech Capital, L.P., a limited partnership of which the sole general partner is Baker Biotech Capital (GP), LLC, due to their interest in 667 and Baker Biotech Capital, L.P.'s right to receive an allocation of a portion of the profits from 667.
Footnote F4
Pursuant to the policies of the Adviser, Felix J. Baker does not have any right to any of the Issuer's securities issued as compensation for his current service on the Board and Ranjeev Krishana and Michael Goller do not have the right to any of the Issuer's securities issued as compensation for their past service on the Board and the Funds are entitled to an indirect proportionate pecuniary interest in such securities.
Footnote F5
The Funds each own an indirect proportionate pecuniary interest in the Ordinary Shares or ADS received upon vesting of restricted share units (each an "RSU"), Share Options, and Ordinary Shares or ADS received upon the exercise of Share Options, in each case that were received as a result of Felix J. Baker's current or Ranjeev Krishana's and Michael Goller's past service on the Board. Solely as a result of their ownership interest in (i) the general partners of the Funds and (ii) the Funds, Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in the Ordinary Shares or ADS received upon vesting of RSUs, Share Options, and Ordinary Shares or ADS received upon the exercise of Share Options (i.e., no direct pecuniary interest).
Footnote F6
The Adviser serves as the investment adviser to the Funds. In connection with the services provided by the Adviser, the Adviser receives an asset-based management fee that does not confer any pecuniary interest in the securities held directly by the Funds or for the benefit of the Funds. Baker Bros. Advisors (GP) LLC (the "Adviser GP") is the Adviser's sole general partner. Julian C. Baker and Felix J. Baker are managing members of the Adviser GP. The Adviser has complete and unlimited discretion and authority with respect to the investment and voting power of the securities held directly by the Funds or for the benefit of the Funds. The general partners of the Funds relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held directly by the Funds or for the benefit of the Funds.
Footnote F7
Julian C. Baker, Felix J. Baker, the Adviser GP and the Adviser disclaim beneficial ownership of the securities held directly by or held for the benefit of the Funds except to the extent of their pecuniary interest therein, and this report shall not be deemed an admission that any of Julian C. Baker, Felix J. Baker, the Adviser GP or the Adviser is a beneficial owner of such securities for purposes of Section 16 or any other purpose.
Footnote F8
Pursuant to the policies of the Adviser, the Adviser has voting and dispositive power over the Share Options, RSUs and any Ordinary Shares or ADS received as a result of the exercise of Share Options or vesting of RSUs.
Footnote F9
Felix J. Baker serves on the Board as a representative of the Funds and their affiliates and control persons.
Footnote F10
Includes beneficial ownership of 71,279 Ordinary Shares received from vested RSUs previously granted to Michael Goller and 71,266 Ordinary Shares received from vested RSUs previously granted to Ranjeev Krishana in their capacity as prior directors of the Issuer and 18,980 Ordinary Shares underlying 18,980 unvested RSUs granted to Felix J. Baker in his capacity as a director of the Issuer.
Footnote F11
After giving effect to the transaction reported herein and as a result of their ownership interest in (i) Baker Brothers Life Sciences Capital, L.P. and (ii) Life Sciences, Julian C. Baker and Felix J. Baker each may be deemed to have an indirect pecuniary interest in securities reported in column 5 of Table I and in column 9 of Table II held directly by or held for the benefit of Life Sciences, a limited partnership of which the sole general partner is Baker Brothers Life Sciences Capital, L.P., a limited partnership of which the sole general partner is Baker Brothers Life Sciences Capital (GP), LLC, due to their interest in Life Sciences and Baker Brothers Life Sciences Capital, L.P.'s right to receive an allocation of a portion of the profits from Life Sciences.
Footnote F12
Ordinary Share held directly by Felix J. Baker.
Footnote F13
Ordinary Share held directly by Julian C. Baker.
Footnote F14
Each ADS represents 13 Ordinary Shares.
Footnote F15
ADS held directly by Felix J. Baker.
Footnote F16
ADS held directly by Julian C. Baker.
Footnote F17
The Share Options vested in 3 equal annual installments on April 19, 2018, April 19, 2019 and April 19, 2020.
Footnote F18
The ADS reported represent a total of 30,768 ADS received upon exercise of 15,384 Share Options issued to each of Ranjeev Krishana and Michael Goller. This amount is reported for each of the Funds as each has an indirect proportionate pecuniary interest in such securities.
SEC remarks
Felix J. Baker, a managing member of Baker Bros. Advisors (GP) LLC , the sole general partner of Baker Bros. Advisors LP, is a director of BeOne Medicines Ltd. (the "Issuer"). By virtue of their representation on the board of directors of the Issuer, for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, the reporting persons other than Felix J. Baker are deemed directors by deputization of the Issuer.