Opaleye Management Inc. - 14 Jul 2026 Form 4/A - Amendment Insider Report for Eton Pharmaceuticals, Inc. (ETON)

Reporting relationship: 10%+ Owner
Issuer ticker: ETON
Reported as of: 14 Jul 2026
Net transaction value: -$1,063,033
SEC form: 4/A - Amendment
Accepted by SEC: 17 Jul 2026, 19:12:15 UTC
Original report date: 16 Jul 2026
Prior SEC filing: 15 Jul 2026
Next SEC filing: 24 Jul 2026
Source filing: View source filing
Reporting owner signature: Opaleye Management, Inc., By: /s/ James Silverman, President

Key filing fact

Opaleye Management Inc. filed Form 4/A - Amendment for Eton Pharmaceuticals, Inc. (ETON) on 17 Jul 2026.

Key facts

This page summarizes Opaleye Management Inc.'s Form 4/A - Amendment filing for Eton Pharmaceuticals, Inc. (ETON).
2 reported transactions and 0 derivative rows are listed below.
Accepted by SEC: 17 Jul 2026, 19:12.

Change

Previous filing in this sequence was filed on 15 Jul 2026.
Current net transaction value: -$1,063,033.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4/A - Amendment disclosures.

View source filing

Reporting Owners (1)

CIK 0001595855 Primary reporting owner

Opaleye Management Inc.

Relationship: 10%+ Owner
Address: ONE BOSTON PLACE, 26TH FLOOR, BOSTON
Signature: Opaleye Management, Inc., By: /s/ James Silverman, President
Signature date: 17 Jul 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

ETON transaction

Common Stock, par value $0.001 per share

Sale

Transaction value: $563,146
Shares: -15,000
Change %: -0.56%
Price: $37.54
Shares after: 2,665,000
Date: 14 Jul 2026
Ownership: By Opaleye, L.P.
Footnotes: F1, F3, F4

ETON transaction

Common Stock, par value $0.001 per share

Sale

Transaction value: $499,886
Shares: -13,315
Change %: -25%
Price: $37.54
Shares after: 40,000
Date: 14 Jul 2026
Ownership: By Managed Account
Footnotes: F2, F3, F4

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Section 16 status

Opaleye Management Inc. is no longer subject to Section 16 filing requirements. Form 4 or Form 5 obligations may still apply in specific circumstances.

Explanation of responses 4 footnotes

Footnote F1

Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund.

Footnote F2

Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Managed Account.

Footnote F3

The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $37.0152 to $37.9148 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.

Footnote F4

Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC remarks

This amendment is filed solely to check the box indicating that the reporting person is no longer subject to Section 16.