MICHAEL THOMAS HENDERSON - 21 Jan 2026 Form 4 Insider Report for Spyre Therapeutics, Inc. (SYRE)

Role
Director
Signature
/s/ Heidy King-Jones, as Attorney-in-Fact
Issuer symbol
SYRE
Transactions as of
21 Jan 2026
Net transactions value
$0
Form type
4
Filing time
23 Jan 2026, 21:31:12 UTC
Previous filing
16 Jan 2026
Next filing
13 Feb 2026

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
HENDERSON MICHAEL THOMAS Director 221 CRESCENT STREET, BUILDING 23,, SUITE 105, WALTHAM /s/ Heidy King-Jones, as Attorney-in-Fact 23 Jan 2026 0001779990

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction SYRE Common Stock Other $0 +63,227 +60% $0.000000 168,606 21 Jan 2026 Direct F1
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 Represents the pro-rata distribution of shares of common stock for no consideration from a limited liability company in which the Reporting Person is a member.