Insider Trading & Ownership of Michael Henderson

Location: Palo Alto, CA
Summary: The estimated net worth of Michael Henderson is at least $96.8M dollars as of December 12, 2025. Michael Henderson is the Chief Executive Officer, Director of Apogee Therapeutics, Inc. and owns shares of Apogee Therapeutics, Inc. (APGE) stock worth about $92.9M. Michael Henderson is the Director of Spyre Therapeutics, Inc. and owns shares of Spyre Therapeutics, Inc. (SYRE) stock worth about $3.87M.
Signature: /s/ Matthew Batters, as attorney-in-fact for Michael Henderson
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Ownership of Michael Henderson

Symbol	Company	Relationship	Holdings Value	Past Year Net Change	Change %	Report Period
APGE	Apogee Therapeutics, Inc.	Chief Executive Officer, Director	$92.9M	-$7.41M	-7.39%	Dec 10, 2025
SYRE	Spyre Therapeutics, Inc.	Director	$3.87M			May 29, 2025
ARYD	ARYA Sciences Acquisition Corp IV	Director				Jul 31, 2024

Sym	Company	Class	Transaction	%	Value $	* Price $	Shares	Shares After	Date	Ownership

* An asterisk sign (*) next to the price indicates that the price is likely invalid.