| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| EDGEMOND JAMES | CFO AND TREASURER | C/O UNITED THERAPEUTICS CORPORATION, 1000 SPRING STREET, SILVER SPRING | /s/ John S. Hess, Jr. under Power of Attorney | 18 Nov 2025 | 0001636178 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | UTHR | Common Stock | Options Exercise | $1,560,769 | +10,688 | +132% | $146.03 | 18,806 | 17 Nov 2025 | Direct | F1 |
| transaction | UTHR | Common Stock | Sale | $1,688,978 | -3,591 | -19% | $470.34 | 15,215 | 17 Nov 2025 | Direct | F1, F2 |
| transaction | UTHR | Common Stock | Sale | $1,252,030 | -2,657 | -17% | $471.22 | 12,558 | 17 Nov 2025 | Direct | F1, F3 |
| transaction | UTHR | Common Stock | Sale | $943,786 | -1,999 | -16% | $472.13 | 10,559 | 17 Nov 2025 | Direct | F1, F4 |
| transaction | UTHR | Common Stock | Sale | $435,783 | -920 | -8.7% | $473.68 | 9,639 | 17 Nov 2025 | Direct | F1, F5 |
| transaction | UTHR | Common Stock | Sale | $303,397 | -639 | -6.6% | $474.80 | 9,000 | 17 Nov 2025 | Direct | F1, F6 |
| transaction | UTHR | Common Stock | Sale | $379,761 | -798 | -8.9% | $475.89 | 8,202 | 17 Nov 2025 | Direct | F1, F7 |
| transaction | UTHR | Common Stock | Sale | $40,024 | -84 | -1% | $476.47 | 8,118 | 17 Nov 2025 | Direct | F1, F8 |
| transaction | UTHR | Common Stock | Options Exercise | $1,505,861 | +10,312 | +127% | $146.03 | 18,430 | 17 Nov 2025 | Direct | F1 |
| transaction | UTHR | Common Stock | Sale | $55,726 | -120 | -0.65% | $464.38 | 18,310 | 17 Nov 2025 | Direct | F1, F9 |
| transaction | UTHR | Common Stock | Sale | $509,602 | -1,090 | -6% | $467.53 | 17,220 | 17 Nov 2025 | Direct | F1, F10 |
| transaction | UTHR | Common Stock | Sale | $1,923,425 | -4,107 | -24% | $468.33 | 13,113 | 17 Nov 2025 | Direct | F1, F11 |
| transaction | UTHR | Common Stock | Sale | $2,139,487 | -4,558 | -35% | $469.39 | 8,555 | 17 Nov 2025 | Direct | F1, F12 |
| transaction | UTHR | Common Stock | Sale | $205,537 | -437 | -5.1% | $470.34 | 8,118 | 17 Nov 2025 | Direct | F1, F2 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | UTHR | Stock Option | Options Exercise | $0 | -10,312 | -100% | $0.000000 | 0 | 17 Nov 2025 | Common Stock | 10,312 | $146.03 | Direct | F1 |
| transaction | UTHR | Stock Option | Options Exercise | $0 | -10,688 | -33% | $0.000000 | 21,517 | 17 Nov 2025 | Common Stock | 10,688 | $146.03 | Direct | F1 |
Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.
Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).
| Id | Content |
|---|---|
| F1 | This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on August 5, 2025. |
| F10 | This transaction was executed in multiple trades at prices ranging from $466.835 to $467.83. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F11 | This transaction was executed in multiple trades at prices ranging from $467.835 to $468.82. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F12 | This transaction was executed in multiple trades at prices ranging from $468.84 to $469.83. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F2 | This transaction was executed in multiple trades at prices ranging from $469.87 to $470.86. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F3 | This transaction was executed in multiple trades at prices ranging from $470.88 to $471.82. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F4 | This transaction was executed in multiple trades at prices ranging from $471.92 to $472.87. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F5 | This transaction was executed in multiple trades at prices ranging from $473.17 to $474.16. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F6 | This transaction was executed in multiple trades at prices ranging from $474.34 to $475.33. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F7 | This transaction was executed in multiple trades at prices ranging from $475.34 to $476.28. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F8 | This transaction was executed in multiple trades at prices ranging from $476.43 to $476.58. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F9 | This transaction was executed in multiple trades at prices ranging from $463.67 to $464.61. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |