| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| EDGEMOND JAMES | CFO AND TREASURER | C/O UNITED THERAPEUTICS CORPORATION, 1000 SPRING STREET, SILVER SPRING | /s/ John S. Hess, Jr. under Power of Attorney | 26 Nov 2025 | 0001636178 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | UTHR | Common Stock | Options Exercise | $3,066,630 | +21,000 | +258% | $146.03 | 29,142 | 24 Nov 2025 | Direct | F1 |
| transaction | UTHR | Common Stock | Sale | $448,658 | -960 | -3.3% | $467.35 | 28,182 | 24 Nov 2025 | Direct | F1, F2 |
| transaction | UTHR | Common Stock | Sale | $866,330 | -1,850 | -6.6% | $468.29 | 26,332 | 24 Nov 2025 | Direct | F1, F3 |
| transaction | UTHR | Common Stock | Sale | $728,414 | -1,552 | -5.9% | $469.34 | 24,780 | 24 Nov 2025 | Direct | F1, F4 |
| transaction | UTHR | Common Stock | Sale | $1,372,575 | -2,919 | -12% | $470.22 | 21,861 | 24 Nov 2025 | Direct | F1, F5 |
| transaction | UTHR | Common Stock | Sale | $930,076 | -1,971 | -9% | $471.88 | 19,890 | 24 Nov 2025 | Direct | F1, F6 |
| transaction | UTHR | Common Stock | Sale | $845,233 | -1,788 | -9% | $472.73 | 18,102 | 24 Nov 2025 | Direct | F1, F7 |
| transaction | UTHR | Common Stock | Sale | $132,592 | -280 | -1.5% | $473.54 | 17,822 | 24 Nov 2025 | Direct | F1, F8 |
| transaction | UTHR | Common Stock | Sale | $741,168 | -1,560 | -8.8% | $475.11 | 16,262 | 24 Nov 2025 | Direct | F1, F9 |
| transaction | UTHR | Common Stock | Sale | $771,745 | -1,621 | -10% | $476.09 | 14,641 | 24 Nov 2025 | Direct | F1, F10 |
| transaction | UTHR | Common Stock | Sale | $1,426,403 | -2,989 | -20% | $477.22 | 11,652 | 24 Nov 2025 | Direct | F1, F11 |
| transaction | UTHR | Common Stock | Sale | $779,362 | -1,630 | -14% | $478.14 | 10,022 | 24 Nov 2025 | Direct | F1, F12 |
| transaction | UTHR | Common Stock | Sale | $150,800 | -315 | -3.1% | $478.73 | 9,707 | 24 Nov 2025 | Direct | F1, F13 |
| transaction | UTHR | Common Stock | Sale | $307,655 | -640 | -6.6% | $480.71 | 9,067 | 24 Nov 2025 | Direct | F1, F14 |
| transaction | UTHR | Common Stock | Sale | $382,354 | -794 | -8.8% | $481.55 | 8,273 | 24 Nov 2025 | Direct | F1, F15 |
| transaction | UTHR | Common Stock | Sale | $63,181 | -131 | -1.6% | $482.29 | 8,142 | 24 Nov 2025 | Direct | F1, F16 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | UTHR | Stock Option | Options Exercise | $0 | -21,000 | -98% | $0.000000 | 517 | 24 Nov 2025 | Common Stock | 21,000 | $146.03 | Direct | F1 |
Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.
Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).
| Id | Content |
|---|---|
| F1 | This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on August 5, 2025. |
| F10 | This transaction was executed in multiple trades at prices ranging from $475.60 to $476.56. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F11 | This transaction was executed in multiple trades at prices ranging from $476.63 to $477.55. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F12 | This transaction was executed in multiple trades at prices ranging from $477.63 to $478.58. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F13 | This transaction was executed in multiple trades at prices ranging from $478.63 to $478.86. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F14 | This transaction was executed in multiple trades at prices ranging from $480.10 to $481.08. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F15 | This transaction was executed in multiple trades at prices ranging from $481.18 to $482.12. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F16 | This transaction was executed in multiple trades at prices ranging from $482.21 to $482.42. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F2 | This transaction was executed in multiple trades at prices ranging from $466.72 to $467.60. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F3 | This transaction was executed in multiple trades at prices ranging from $467.72 to $468.71. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F4 | This transaction was executed in multiple trades at prices ranging from $468.76 to $469.75. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F5 | This transaction was executed in multiple trades at prices ranging from $469.77 to $470.73. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F6 | This transaction was executed in multiple trades at prices ranging from $471.33 to $472.31. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F7 | This transaction was executed in multiple trades at prices ranging from $472.34 to $473.22. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F8 | This transaction was executed in multiple trades at prices ranging from $473.40 to $474.04. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F9 | This transaction was executed in multiple trades at prices ranging from $474.55 to $475.49. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |