| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Zanganeh Mahkam | Co-Chief Executive Officer, Director, 10%+ Owner | C/O SUMMIT THERAPEUTICS INC., 601 BRICKELL KEY DRIVE, SUITE 1000, MIAMI | /s/ Mahkam Zanganeh | 11 Sep 2025 | 0001507650 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | SMMT | Common Stock | Purchase | $5,894,406 | +333,394 | +0.06% | $17.68 | 556,088,090 | 10 Sep 2025 | By Spouse | F1, F2 |
| transaction | SMMT | Common Stock | Purchase | $90,350 | +5,000 | +0% | $18.07 | 556,093,090 | 11 Sep 2025 | By Spouse | F2 |
| holding | SMMT | Common Stock | 10,199,776 | 10 Sep 2025 | By the Shaun Zanganeh Irrevocable Trust, with the Reporting Person as Trustee | F2 | |||||
| holding | SMMT | Common Stock | 25,457,666 | 10 Sep 2025 | By the Mahkam Zanganeh Revocable Trust, with the Reporting Person as Trustee | F2 | |||||
| holding | SMMT | Common Stock | 50,000 | 10 Sep 2025 | Immediate family member | F2 | |||||
| holding | SMMT | Common Stock | 31,000 | 10 Sep 2025 | Direct |
| Id | Content |
|---|---|
| F1 | The reported price in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $17.49 to $17.89 per share, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote. |
| F2 | The Reporting Person disclaims beneficial ownership of these securities, except to the extent of her pecuniary interest therein, if any, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 or for any other purpose |