Theodore James Jr. Washburn - 01 Mar 2026 Form 4 Insider Report for AGIOS PHARMACEUTICALS, INC. (AGIO)

Role
Principal Accounting Officer
Signature
/s/ William Cook, as attorney-in-fact for Theodore James Jr. Washburn
Issuer symbol
AGIO
Transactions as of
01 Mar 2026
Net transactions value
-$64,378
Form type
4
Filing time
03 Mar 2026, 16:12:38 UTC
Previous filing
09 Sep 2025
Next filing
05 Mar 2026
SEC
View on sec.gov

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Washburn Theodore James Jr. Principal Accounting Officer 88 SIDNEY STREET, CAMBRIDGE /s/ William Cook, as attorney-in-fact for Theodore James Jr. Washburn 03 Mar 2026 0001874199

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction AGIO Common stock Options Exercise $0 +2,350 +249% $0.000000 3,293 02 Mar 2026 Direct F1
transaction AGIO Common stock Sale $20,214 -698 -21% $28.96 2,595 02 Mar 2026 Direct F2
transaction AGIO Common stock Options Exercise $0 +2,450 +97% $0.000000 4,970 02 Mar 2026 Direct
transaction AGIO Common stock Sale $21,054 -727 -15% $28.96 4,243 02 Mar 2026 Direct F3
transaction AGIO Common stock Options Exercise $0 +2,695 +64% $0.000000 6,938 02 Mar 2026 Direct
transaction AGIO Common stock Sale $23,110 -798 -12% $28.96 6,140 02 Mar 2026 Direct F4

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction AGIO Restricted stock units Award $0 +8,452 $0.000000 8,452 01 Mar 2026 Common stock 8,452 Direct F5, F6
transaction AGIO Restricted stock units Options Exercise $0 -2,350 -100% $0.000000 0 02 Mar 2026 Common stock 2,350 Direct F5, F7
transaction AGIO Restricted stock units Options Exercise $0 -2,450 -50% $0.000000 2,450 02 Mar 2026 Common stock 2,450 Direct F5, F8
transaction AGIO Restricted stock units Options Exercise $0 -2,695 -33% $0.000000 5,390 02 Mar 2026 Common stock 2,695 Direct F5, F9
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 Includes 75 shares purchased through the Company's employee stock purchase plan.
F2 Shares sold to cover the tax withholding obligation in respect of vesting of the reporting person's restricted stock units. This transaction was effected pursuant to durable automatic sale instructions consistent with the affirmative defense to liability under Section 10(b) of the Securities Exchange Act of 1934 under Rule 10b5-1(c) promulgated under such Act. Such instructions were included in the reporting person's restricted stock unit agreement dated March 1, 2023.
F3 Shares sold to cover the tax withholding obligation in respect of vesting of the reporting person's restricted stock units. This transaction was effected pursuant to durable automatic sale instructions consistent with the affirmative defense to liability under Section 10(b) of the Securities Exchange Act of 1934 under Rule 10b5-1(c) promulgated under such Act. Such instructions were included in the reporting person's restricted stock unit agreement dated March 1, 2024.
F4 Shares sold to cover the tax withholding obligation in respect of vesting of the reporting person's restricted stock units. This transaction was effected pursuant to durable automatic sale instructions consistent with the affirmative defense to liability under Section 10(b) of the Securities Exchange Act of 1934 under Rule 10b5-1(c) promulgated under such Act. Such instructions were included in the reporting person's restricted stock unit agreement dated March 1, 2025.
F5 Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.
F6 The restricted stock units were granted on March 1, 2026. Beginning on March 1, 2027, the shares underlying the restricted stock units will vest in three equal annual installments.
F7 The restricted stock units were granted on March 1, 2023. Beginning on March 1, 2024, the shares underlying the restricted stock units will vest in three equal annual installments.
F8 The restricted stock units were granted on March 1, 2024. Beginning on March 1, 2025, the shares underlying the restricted stock units will vest in three equal annual installments.
F9 The restricted stock units were granted on March 1, 2025. Beginning on March 1, 2026, the shares underlying the restricted stock units will vest in three equal annual installments.