| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Washburn Theodore James Jr. | Principal Accounting Officer | 88 SIDNEY STREET, CAMBRIDGE | /s/ William Cook, as attorney-in-fact for Theodore James Jr. Washburn | 09 Sep 2025 | 0001874199 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | AGIO | Common stock | Sale | $315,091 | -8,546 | -91% | $36.87 | 868 | 05 Sep 2025 | Direct |