| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Washburn Theodore James Jr. | Principal Accounting Officer | 88 SIDNEY STREET, CAMBRIDGE | /s/ William Cook, as attorney-in-fact for Theodore James Jr. Washburn | 05 Mar 2026 | 0001874199 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | AGIO | Common stock | Sale | $152,255 | -5,272 | -86% | $28.88 | 868 | 03 Mar 2026 | Direct |