| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| BRYNJELSEN SEAN | President & CEO, Director, 10%+ Owner | C/O ETON PHARMACEUTICALS, INC., 21925 W. FIELD PARKWAY, SUITE 235, DEERPARK | /s/ James R. Gruber | 14 Jan 2026 | 0001669976 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ETON | Common Stock | Tax liability | $77,181 | -5,015 | -0.17% | $15.39 | 2,889,266 | 01 Jan 2026 | Direct | F1, F2, F3 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ETON | Employee Stock Option (Right to Buy) | Award | $0 | +158,046 | +5.5% | $0.000000 | 3,047,312 | 12 Jan 2026 | Common Stock | 158,046 | $15.47 | Direct | F4 |
| transaction | ETON | Restricted Stock Units | Award | $0 | +100,517 | +3.3% | $0.000000 | 3,147,829 | 12 Jan 2026 | Common Stock | 100,517 | Direct | F5, F6 |
| Id | Content |
|---|---|
| F1 | Shares withheld by the Issuer to satisfy applicable withholding taxes upon the vesting of restricted stock units. |
| F2 | The shares were sold in multiple trades at prices ranging from $15.39 to $15.42. The price reported above reflects the weighted average sales price. |
| F3 | The Reporting Person will provide upon request by the Securities and Exchange Commission staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased or sold at each separate price. |
| F4 | The shares subject to the option shall vest in 48 equal monthly installments from the date of grant until fully vested and exercisable on January 12, 2030. |
| F5 | Each restricted stock unit represents a contingent right to receive one share of ETON Common Stock. |
| F6 | The restricted stock units vest in four equal annual installments beginning January 12, 2027, contingent upon the reporting person being employed by the issuer on the date(s) of vesting. |
The reporting person has authorized and designated the named person to file this Form 4 on the reporting person's behalf for indefinite duration.