| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| AKKARAJU SRINIVAS | Director | 628 MIDDLEFIELD ROAD, PALO ALTO | /s/ Srinivas Akkaraju | 07 Oct 2025 | 0001253170 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | SRRK | Common Stock | Purchase | $392,102 | +11,011 | $35.61 | 11,011 | 03 Oct 2025 | By Samsara Opportunity Fund, L.P. | F1, F2 | |
| transaction | SRRK | Common Stock | Purchase | $2,083,268 | +56,703 | +515% | $36.74 | 67,714 | 03 Oct 2025 | By Samsara Opportunity Fund, L.P. | F2, F3 |
| transaction | SRRK | Common Stock | Purchase | $11,963,174 | +319,700 | +472% | $37.42 | 387,414 | 03 Oct 2025 | By Samsara Opportunity Fund, L.P. | F2, F4 |
| transaction | SRRK | Common Stock | Purchase | $697,706 | +18,414 | +4.8% | $37.89 | 405,828 | 06 Oct 2025 | By Samsara Opportunity Fund, L.P. | F5 |
| transaction | SRRK | Common Stock | Purchase | $3,127,781 | +80,863 | +20% | $38.68 | 486,691 | 06 Oct 2025 | By Samsara Opportunity Fund, L.P. | F2, F6 |
| transaction | SRRK | Common Stock | Purchase | $543,321 | +13,748 | +2.8% | $39.52 | 500,439 | 06 Oct 2025 | By Samsara Opportunity Fund, L.P. | F2, F7 |
| holding | SRRK | Common Stock | 21,132 | 03 Oct 2025 | Direct | ||||||
| holding | SRRK | Common Stock | 5,302,810 | 03 Oct 2025 | Samsara BioCapital, L.P. | F8, F9 |
| Id | Content |
|---|---|
| F1 | The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $35.14 to $36.13 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities purchased at each separate price within the range set forth in this footnote. |
| F2 | Securities are directly held by Samsara Opportunity Fund, L.P. ("Samsara Opportunity Fund"). Samsara Opportunity Fund GP, LLC ("Samsara Opportunity GP") is the general partner of Samsara Opportunity Fund and may be deemed to beneficially own the securities held by Samsara Opportunity Fund. The Reporting Person has voting and investment power over the shares held by Samsara Opportunity Fund and, accordingly, may be deemed to beneficially own the shares held by Samsara Opportunity Fund. The Reporting Person disclaims beneficial ownership in these securities except to the extent of his pecuniary interest therein. |
| F3 | The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $36.14 to $37.1391 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities purchased at each separate price within the range set forth in this footnote. |
| F4 | The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $37.14 to $37.6227 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities purchased at each separate price within the range set forth in this footnote. |
| F5 | The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $37.23 to $38.2276 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities purchased at each separate price within the range set forth in this footnote. |
| F6 | The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $38.23 to $39.2298 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities purchased at each separate price within the range set forth in this footnote. |
| F7 | The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $39.23 to $39.84 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities purchased at each separate price within the range set forth in this footnote. |
| F8 | The shares held by Samsara BioCapital, L.P. ("Samsara LP") reflect the disposition of 310,086 shares previously reported as held by Samsara LP, in which the Reporting Person had no pecuniary interest. The transfer of such shares by Samsara LP did not involve a change in the Reporting Person's beneficial ownership of such shares and, accordingly, was exempt from reporting under Section 16. |
| F9 | Shares held by Samsara LP. The Reporting Person is a managing member of Samsara BioCapital GP, LLC, the general partner of Samsara LP. The Reporting Person disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein. |