Mark Coleman - 10 Feb 2026 Form 4 Insider Report for Axsome Therapeutics, Inc. (AXSM)

Role: Director
Signature: /s/ Nick Pizzie, Attorney-in-Fact
Issuer symbol: AXSM
Transactions as of: 10 Feb 2026
Net transactions value: +$41,648
Form type: 4
Filing time: 10 Feb 2026, 19:11:27 UTC
Previous filing: 09 Sep 2025
Next filing: 23 Feb 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Coleman Mark	Director	C/O AXSOME THERAPEUTICS, INC., ONE WORLD TRADE CENTER, 29TH FLOOR, NEW YORK	/s/ Nick Pizzie, Attorney-in-Fact	10 Feb 2026	0001658379

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	AXSM	Common Stock	Options Exercise	$41,648	+5,193	+11%	$8.02	53,405	10 Feb 2026	Direct	F1
holding	AXSM	Common Stock						403,856	10 Feb 2026	See Footnote	F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	AXSM	Stock Option (Right to Buy)	Options Exercise	$0	-5,193	-100%	$0.000000	0	10 Feb 2026	Common Stock	5,193	$8.02	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Represents the exercise of stock options, prior to the 10-year expiration date, for cash and hold of underlying shares.
F2	Such shares are held by an entity, of which the reporting person has voting and dispositive power, and therefore, the reporting person is deemed to be the indirect beneficial owner of such shares.