MICHAEL THOMAS HENDERSON - 02 Jan 2026 Form 4 Insider Report for Apogee Therapeutics, Inc. (APGE)

Role: Chief Executive Officer, Director
Signature: /s/ Matthew Batters, as attorney-in-fact for Michael Henderson
Issuer symbol: APGE
Transactions as of: 02 Jan 2026
Net transactions value: $0
Form type: 4
Filing time: 06 Jan 2026, 20:01:52 UTC
Previous filing: 12 Dec 2025
Next filing: 16 Jan 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
HENDERSON MICHAEL THOMAS	Chief Executive Officer, Director	C/O APOGEE THERAPEUTICS, INC., 221 CRESCENT ST., BLDG. 17, STE. 102B, WALTHAM	/s/ Matthew Batters, as attorney-in-fact for Michael Henderson	06 Jan 2026	0001779990

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	APGE	Stock Option (Right to Buy)	Award	$0	+253,016		$0.000000	253,016	02 Jan 2026	Common Stock	253,016	$75.78	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	This option represents the right to purchase 253,016 shares of the Issuer's common stock, which will vest in forty-eight equal monthly installments over a four-year period from the date of grant, subject to the Reporting Person's continued service to the Issuer.