| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ETNB | Pre-Funded Warrants (Right to Buy) | Purchase | $9,998,918 | +1,081,081 | $9.25 | 1,081,081 | 11 Dec 2023 | Common Stock | 1,081,081 | $0.001000 | See Footnotes | F1, F2, F3, F4 |
| Id | Content |
|---|---|
| F1 | The Pre-Funded Warrants have no expiration date and are exercisable immediately and will be exercisable until exercise. The Pre-Funded Warrants may not be exercised to the extent such exercise would cause the holder (together with its affiliates, any other persons acting as a group together with the holder or any of the holder's affiliates, and any other persons whose beneficial ownership of the issuer's Common Stock would or could be aggregated with the holder's for purposes of Section 13(d) or Section 16 of the Securities Exchange Act of 1934, as amended) to beneficially own more than 9.99% of the Issuer's Common Stock outstanding immediately after giving effect to such exercise. |
| F2 | Acquired from the Issuer pursuant to the public offering described in the Issuer's Prospectus filed with the Securities and Exchange Commission on December 8, 2023. |
| F3 | Held directly by RA Capital Healthcare Fund, L.P. (the "Fund"). |
| F4 | RA Capital Management, L.P. (the "Adviser") is the investment manager for the Fund and RA Capital Nexus Fund, L.P. The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. The Adviser, the Adviser GP, Dr. Kolchinsky, and Mr. Shah disclaim beneficial ownership of any of the reported securities, except to the extent of their pecuniary interest therein. |
Mr. Derek DiRocco, a Partner of the Adviser, serves on the Issuer's board of directors.