| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | SPRY | Common Stock | Purchase | $7,450,812 | +2,508,691 | +43% | $2.97 | 8,365,465 | 21 Sep 2023 | See Footnotes | F1, F2, F6 |
| transaction | SPRY | Common Stock | Purchase | $732,713 | +191,309 | +2.3% | $3.83 | 8,556,774 | 21 Sep 2023 | See Footnotes | F3, F4, F6 |
| holding | SPRY | Common Stock | 902,904 | 21 Sep 2023 | See Footnotes | F5, F6 |
| Id | Content |
|---|---|
| F1 | This transaction was executed in multiple trades at prices ranging from $2.75 to $3.74; the price reported above reflects the weighted average purchase price. The reporting person hereby undertakes, upon request, to provide full information to the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer regarding the number of shares and prices at which these transactions, and all other transactions reported in this Form 4, were effected. |
| F2 | Held directly by RA Capital Healthcare Fund, L.P. (the "Fund"). |
| F3 | This transaction was executed in multiple trades at prices ranging from $3.75 to $3.90; the price reported above reflects the weighted average purchase price. The reporting person hereby undertakes, upon request, to provide full information to the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer regarding the number of shares and prices at which these transactions, and all other transactions reported in this Form 4, were effected. |
| F4 | Held directly by the Fund. |
| F5 | Held directly by RA Capital Nexus Fund II, L.P. (the "Nexus Fund II"). |
| F6 | RA Capital Management, L.P. (the "Adviser") is the investment manager for the Fund and the Nexus Fund II. The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. The Adviser, the Adviser GP, Dr. Kolchinsky, and Mr. Shah disclaim beneficial ownership of any of the reported securities, except to the extent of their pecuniary interest therein. |
Dr. Peter Kolchinsky, a Managing Partner of the Adviser, serves on the Issuer's board of directors.