| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| LEIDEN JEFFREY M | Executive Chairman, Director | C/O VERTEX PHARMACEUTICALS INCORPORATED, 50 NORTHERN AVENUE, BOSTON | /s/ Christiana Stevenson, Attorney-in-Fact | 19 Feb 2026 | 0001242825 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | VRTX | Common Stock | Award | $0 | +8,269 | +25% | $0.000000 | 41,308 | 17 Feb 2026 | Direct | F1 |
| transaction | VRTX | Common Stock | Tax liability | $1,433,835 | -2,964 | -7.2% | $483.75 | 38,344 | 18 Feb 2026 | Direct | |
| holding | VRTX | Common Stock | 440 | 17 Feb 2026 | 401(k) |
| Id | Content |
|---|---|
| F1 | Restricted stock unit award that fully vested upon grant. |