New Leaf Venture Partners, L.L.C.

Holdings History for Sage Therapeutics, Inc. - Common Stock, par value $0.0001 per share (the "Common Stock") (SAGE)

Symbol: SAGE
Investment type: Equity / Common Stock, par value $0.0001 per share (the "Common Stock")

Shares, Excluding Options vs Price

Value, Excluding Options

Holdings date	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
31 Mar 2018		-1.9%	$0	0	-25,000	-100%	$14.85	Q1 2018
31 Dec 2017	1.9%	-1.5%	$4,118,000	25,000	-19,872	-44%	$164.72	Q4 2017
30 Sep 2017	1.3%	-0.67%	$2,796,000	44,872	-23,000	-34%	$62.31	Q3 2017
30 Jun 2017	4.6%	-2.1%	$5,405,000	67,872	-31,251	-32%	$79.64	Q2 2017
31 Mar 2017	3.6%	-0.55%	$7,045,000	99,123	-15,000	-13%	$71.07	Q1 2017
31 Dec 2016	4.2%	-0.68%	$5,827,000	114,123	-18,551	-14%	$51.06	Q4 2016
30 Sep 2016	4.4%	-0.81%	$6,110,000	132,674	-24,284	-15%	$46.05	Q3 2016
30 Jun 2016	4.1%	+0.37%	$4,729,000	156,958	+14,388	+10%	$30.13	Q2 2016
31 Mar 2016	4.1%	+4.1%	$4,571,000	142,570	+142,570	NEW	$32.06	Q1 2016
31 Dec 2015		-0.87%	$0	0	-23,829	-100%	$14.85	Q4 2015
30 Sep 2015	0.87%	+0.87%	$1,008,000	23,829	+23,829	NEW	$42.30	Q3 2015
30 Jun 2015		-1.5%	$0	0	-43,770	-100%	$14.85	Q2 2015
31 Mar 2015	1.5%	+0.3%	$2,199,000	43,770	+8,400	+24%	$50.24	Q1 2015
31 Dec 2014	0.63%	0%	$1,295,000	35,370	0		$36.61	Q4 2014

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.