Sage Therapeutics, Inc. - Common Stock, par value $0.0001 per share (the "Common Stock") (SAGE)

Q: What does CUSIP 78667J108 represent in this 13F holders report?

CUSIP 78667J108 is the security identifier for SAGE - Sage Therapeutics, Inc. - Common Stock, par value $0.0001 per share (the "Common Stock") used to aggregate holder disclosures.

Q: How many institutions held SAGE - Sage Therapeutics, Inc. - Common Stock, par value $0.0001 per share (the "Common Stock") in Q4 2016?

161 institutional investors reported SAGE - Sage Therapeutics, Inc. - Common Stock, par value $0.0001 per share (the "Common Stock") for Q4 2016. Use the holders table for investor-level position and value details.

CUSIP: 78667J108

Q4 2016 13F Holders as of 31 Dec 2016

Type / Class: Equity / Common Stock, par value $0.0001 per share (the "Common Stock")
Shares outstanding: 62,650,155
Total 13F shares: 36,733,208
Share change: -1,061,964
Total reported value: $1,875,786,404
Put/Call ratio: 124%
Price per share: $51.06
Number of holders: 161
Value change: -$50,072,012
Number of buys: 89
Number of sells: 62

Quarterly Holders Quick Answers

What is CUSIP 78667J108?
CUSIP 78667J108 identifies SAGE - Sage Therapeutics, Inc. - Common Stock, par value $0.0001 per share (the "Common Stock") in SEC institutional holdings data.

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Newer quarter: Q1 2017
Previous quarter: Q3 2016

Recent filing periods for CUSIP 78667J108:

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Top shareholders of SAGE - Sage Therapeutics, Inc. - Common Stock, par value $0.0001 per share (the "Common Stock") (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
FMR LLC	13F	Company	8.7%	5,474,480	$252,100,000	—	30 Sep 2016	13F
VANGUARD GROUP INC	13F	Company	3.7%	2,296,767	$105,767,000	—	30 Sep 2016	13F
OppenheimerFunds, Inc.	13F	Company	3.1%	1,915,874	$88,226,000	—	30 Sep 2016	13F
PRICE T ROWE ASSOCIATES INC /MD/	13F	Company	2.2%	1,401,678	$64,547,000	—	30 Sep 2016	13F
CITADEL ADVISORS LLC	13F	Company	2%	1,274,413	$58,687,000	—	30 Sep 2016	13F
FEDERATED HERMES, INC.	13F	Company	2%	1,224,200	$56,374,000	—	30 Sep 2016	13F
FRANKLIN RESOURCES INC	13F	Company	1.9%	1,210,082	$55,724,000	—	30 Sep 2016	13F
JPMORGAN CHASE & CO	13F	Company	1.9%	1,206,544	$55,562,000	—	30 Sep 2016	13F
BlackRock Fund Advisors	13F	Company	1.9%	1,189,093	$54,758,000	—	30 Sep 2016	13F
STATE STREET CORP	13F	Company	1.9%	1,170,501	$53,904,000	—	30 Sep 2016	13F
OAK RIDGE INVESTMENTS LLC	13F	Company	1.8%	1,154,481	$53,164,000	—	30 Sep 2016	13F
DEUTSCHE BANK AG\	13F	Company	1.6%	1,032,426	$47,542,000	—	30 Sep 2016	13F
BB BIOTECH AG	13F	Company	1.6%	1,022,439	$47,083,000	—	30 Sep 2016	13F
ALLIANCEBERNSTEIN L.P.	13F	Company	1.5%	945,582	$43,544,000	—	30 Sep 2016	13F
Palo Alto Investors LP	13F	Company	1.4%	902,051	$41,539,000	—	30 Sep 2016	13F
JENNISON ASSOCIATES LLC	13F	Company	1.3%	825,744	$38,026,000	—	30 Sep 2016	13F
MILLENNIUM MANAGEMENT LLC	13F	Company	1.2%	722,392	$33,266,000	—	30 Sep 2016	13F
BlackRock Institutional Trust Company, N.A.	13F	Company	1.1%	681,592	$31,387,000	—	30 Sep 2016	13F
LORD, ABBETT & CO. LLC	13F	Company	1.1%	679,048	$31,270,000	—	30 Sep 2016	13F
MARSHALL WACE, LLP	13F	Company	1.1%	673,539	$31,017,000	—	30 Sep 2016	13F
EAGLE ASSET MANAGEMENT INC	13F	Company	1%	630,494	$29,034,000	—	30 Sep 2016	13F
KINGDON CAPITAL MANAGEMENT, L.L.C.	13F	Company	0.81%	506,990	$23,347,000	—	30 Sep 2016	13F
VICTORY CAPITAL MANAGEMENT INC	13F	Company	0.8%	501,558	$23,097,000	—	30 Sep 2016	13F
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	13F	Company	0.62%	390,406	$17,978,000	—	30 Sep 2016	13F
BLACKROCK ADVISORS LLC	13F	Company	0.55%	347,425	$15,999,000	—	30 Sep 2016	13F
PICTET ASSET MANAGEMENT LTD	13F	Company	0.55%	343,429	$15,815,000	—	30 Sep 2016	13F
Granahan Investment Management, LLC	13F	Company	0.5%	316,065	$14,555,000	—	30 Sep 2016	13F
GOLDMAN SACHS GROUP INC	13F	Company	0.5%	311,480	$14,343,000	—	30 Sep 2016	13F
NORTHERN TRUST CORP	13F	Company	0.49%	305,998	$14,091,000	—	30 Sep 2016	13F
VOYA INVESTMENT MANAGEMENT LLC	13F	Company	0.43%	267,938	$12,338,000	—	30 Sep 2016	13F
Casdin Capital, LLC	13F	Company	0.43%	266,500	$12,272,000	—	30 Sep 2016	13F
GREAT POINT PARTNERS LLC	13F	Company	0.42%	264,893	$12,198,000	—	30 Sep 2016	13F
EverPoint Asset Management, LLC	13F	Company	0.4%	250,000	$11,513,000	—	30 Sep 2016	13F
ORBIMED ADVISORS LLC	13F	Company	0.38%	235,400	$10,840,000	—	30 Sep 2016	13F
NORGES BANK	13F	Company	0.39%	243,861	$10,726,000	—	30 Sep 2016	13F
BALYASNY ASSET MANAGEMENT L.P.	13F	Company	0.37%	230,006	$10,592,000	—	30 Sep 2016	13F
FRONTIER CAPITAL MANAGEMENT CO LLC	13F	Company	0.37%	228,954	$10,543,000	—	30 Sep 2016	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	0.36%	225,761	$10,396,000	—	30 Sep 2016	13F
BAKER BROS. ADVISORS LP	13F	Company	0.33%	208,328	$9,594,000	—	30 Sep 2016	13F
Artal Group S.A.	13F	Company	0.32%	200,000	$9,210,000	—	30 Sep 2016	13F
Ghost Tree Capital, LLC	13F	Company	0.28%	175,000	$8,059,000	—	30 Sep 2016	13F
EVENTIDE ASSET MANAGEMENT, LLC	13F	Company	0.27%	170,000	$7,829,000	—	30 Sep 2016	13F
Point72 Asset Management, L.P.	13F	Company	0.27%	166,600	$7,672,000	—	30 Sep 2016	13F
SPHERA FUNDS MANAGEMENT LTD.	13F	Company	0.25%	159,500	$7,345,000	—	30 Sep 2016	13F
Clarius Group, LLC	13F	Company	0.24%	149,068	$6,865,000	—	30 Sep 2016	13F
Tekla Capital Management LLC	13F	Company	0.23%	146,800	$6,760,000	—	30 Sep 2016	13F
Bank of New York Mellon Corp	13F	Company	0.22%	137,267	$6,321,000	—	30 Sep 2016	13F
New Leaf Venture Partners, L.L.C.	13F	Company	0.21%	132,674	$6,110,000	—	30 Sep 2016	13F
BlackRock Investment Management, LLC	13F	Company	0.21%	130,334	$6,002,000	—	30 Sep 2016	13F
CITIGROUP INC	13F	Company	0.21%	128,873	$5,935,000	—	30 Sep 2016	13F

Institutional Holders of Sage Therapeutics, Inc. - Common Stock, par value $0.0001 per share (the "Common Stock") (SAGE) as of Q4 2016

As of 31 Dec 2016, Sage Therapeutics, Inc. - Common Stock, par value $0.0001 per share (the "Common Stock") (SAGE) was held by 161 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 36,733,208 shares. The largest 10 holders included FMR LLC, PRICE T ROWE ASSOCIATES INC /MD/, VANGUARD GROUP INC, OppenheimerFunds, Inc., BlackRock Fund Advisors, STATE STREET CORP, FRANKLIN RESOURCES INC, BB BIOTECH AG, OAK RIDGE INVESTMENTS LLC, and Palo Alto Investors, LLC. This page lists 161 institutional shareholders reporting positions in this security for the Q4 2016 filing period.

Investor	Option	Weight %	Change %	Value $	* Price	Shares	Share Change	Activity	Report Period

Compare Q4 2016 vs Q3 2016 Across Filers

Q3 2016 holders

150

Q4 2016 holders

161

Holder diff

Investor	Q3 2016 Shares	Q4 2016 Shares	Share Diff	Share Chg %	Q3 2016 Value $	Q4 2016 Value $	Value Diff $	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.