| Reporting Name | Ownership % | Change | Value $ | Shares owned | Change | Activity % | Price | Form | Report date | Filing time |
|---|---|---|---|---|---|---|---|---|---|---|
| EcoR1 Capital, LLC | 13% | +12% | $243,919,471 | 8,714,522 | +911,320 | +12% | $27.99 | 13D/A | 24 Jul 2025 | 28 Jul 2025, 20:37 |
| EcoR1 Capital, LLC | 12% | $206,706,821 | 7,803,202 | $26.49 | 13D/A | 15 May 2025 | 19 May 2025, 18:33 |
| Holdings date | Option | Weight | Change | Value $ | Shares | Change | Activity % | Price | All Holders |
|---|---|---|---|---|---|---|---|---|---|
| 31 Dec 2025 | 2.5% | 0% | $54,514,791 | 1,667,119 | 0 | $32.70 | Q4 2025 | ||
| 30 Sep 2025 | 2.8% | +1% | $57,749,002 | 1,667,119 | +630,174 | +61% | $34.64 | Q3 2025 | |
| 30 Jun 2025 | 1.7% | +1.5% | $29,024,091 | 1,036,945 | +881,939 | +569% | $27.99 | Q2 2025 | |
| 31 Mar 2025 | 0.23% | 0% | $3,893,751 | 155,006 | 0 | $25.12 | Q1 2025 | ||
| 31 Dec 2024 | 0.17% | 0% | $4,262,665 | 155,006 | 0 | $27.50 | Q4 2024 | ||
| 30 Sep 2024 | 0.15% | -5.5% | $4,462,623 | 155,006 | -5,601,262 | -97% | $28.79 | Q3 2024 | |
| 30 Jun 2024 | 4.4% | 0% | $142,640,321 | 5,756,268 | 0 | $24.78 | Q2 2024 | ||
| 31 Mar 2024 | 4.7% | 0% | $185,351,830 | 5,756,268 | 0 | $32.20 | Q1 2024 | ||
| 31 Dec 2023 | 6.1% | 0% | $233,992,294 | 5,756,268 | 0 | $40.65 | Q4 2023 | ||
| 30 Sep 2023 | 6.8% | 0% | $198,879,059 | 5,756,268 | 0 | $34.55 | Q3 2023 | ||
| 30 Jun 2023 | 6.2% | +1.6% | $234,049,857 | 5,756,268 | +1,511,623 | +36% | $40.66 | Q2 2023 | |
| 31 Mar 2023 | 5.3% | +0.64% | $164,013,083 | 4,244,645 | +513,915 | +14% | $38.64 | Q1 2023 | |
| 31 Dec 2022 | 5% | +0.72% | $165,569,797 | 3,730,730 | +533,230 | +17% | $44.38 | Q4 2022 | |
| 30 Sep 2022 | 4% | 0% | $136,341,000 | 3,197,500 | 0 | $42.64 | Q3 2022 | ||
| 30 Jun 2022 | 6.2% | +0% | $178,420,000 | 3,197,500 | +1,876 | +0.06% | $55.80 | Q2 2022 | |
| 31 Mar 2022 | 6.2% | +1.9% | $198,193,000 | 3,195,624 | +971,221 | +44% | $62.02 | Q1 2022 | |
| 31 Dec 2021 | 3.9% | +1.2% | $122,631,000 | 2,224,403 | +665,654 | +43% | $55.13 | Q4 2021 | |
| 30 Sep 2021 | 2.9% | +2.9% | $82,006,000 | 1,558,749 | +1,558,749 | NEW | $52.61 | Q3 2021 | |
| 31 Mar 2021 | -0.26% | $0 | 0 | -46,666 | -100% | $33.60 | Q1 2021 | ||
| 31 Dec 2020 | 0.26% | +0.26% | $4,619,000 | 46,666 | +46,666 | NEW | $98.98 | Q4 2020 | |
| 31 Mar 2018 | -1.4% | $0 | 0 | -110,384 | -100% | $33.60 | Q1 2018 | ||
| 31 Dec 2017 | 1.4% | -1.6% | $10,350,000 | 110,384 | -130,392 | -54% | $93.76 | Q4 2017 | |
| 30 Sep 2017 | 3.4% | -4.7% | $24,499,000 | 240,776 | -337,729 | -58% | $101.75 | Q3 2017 | |
| 30 Jun 2017 | 10% | +0.48% | $44,267,000 | 578,505 | +27,464 | +5% | $76.52 | Q2 2017 | |
| 31 Mar 2017 | 13% | -0.25% | $47,494,000 | 551,041 | -10,300 | -1.8% | $86.19 | Q1 2017 | |
| 31 Dec 2016 | 12% | +1.4% | $36,032,000 | 561,341 | +60,765 | +12% | $64.19 | Q4 2016 | |
| 30 Sep 2016 | 12% | +1.5% | $32,367,000 | 500,576 | +61,191 | +14% | $64.66 | Q3 2016 | |
| 30 Jun 2016 | 11% | +4.9% | $24,373,000 | 439,385 | +192,694 | +78% | $55.47 | Q2 2016 | |
| 31 Mar 2016 | 4.2% | +1.3% | $10,317,000 | 246,691 | +79,330 | +47% | $41.82 | Q1 2016 | |
| 31 Dec 2015 | 4.2% | +4.2% | $10,524,000 | 167,361 | +167,361 | NEW | $62.88 | Q4 2015 |