| Reporting Name | Ownership % | Change | Value $ | Shares owned | Change | Activity % | Price | Form | Report date | Filing time |
|---|---|---|---|---|---|---|---|---|---|---|
| Baker Bros. Advisors LP | 11% | +14% | $551,236,913 | 8,676,797 | +2,010,257 | +30% | $63.53 | 13D/A | 09 Dec 2025 | 11 Dec 2025, 17:27 |
| Baker Bros. Advisors LP | 9.5% | $191,996,352 | 6,666,540 | $28.80 | 13D/A | 26 Jun 2025 | 30 Jun 2025, 20:26 |
| Holdings date | Option | Weight | Change | Value $ | Shares | Change | Activity % | Price | All Holders |
|---|---|---|---|---|---|---|---|---|---|
| 31 Dec 2025 | 3.9% | +0.91% | $673,620,000 | 8,657,242 | +2,005,813 | +30% | $77.81 | Q4 2025 | |
| 30 Sep 2025 | 2.7% | 0% | $376,470,881 | 6,651,429 | 0 | $56.60 | Q3 2025 | ||
| 30 Jun 2025 | 2.8% | +0.28% | $290,268,362 | 6,651,429 | +655,500 | +11% | $43.64 | Q2 2025 | |
| 31 Mar 2025 | 1.8% | 0% | $164,108,577 | 5,995,929 | 0 | $27.37 | Q1 2025 | ||
| 31 Dec 2024 | 2.6% | 0% | $241,216,224 | 5,995,929 | 0 | $40.23 | Q4 2024 | ||
| 30 Sep 2024 | 2.9% | 0% | $283,787,320 | 5,995,929 | +1 | +0% | $47.33 | Q3 2024 | |
| 30 Jun 2024 | 2.3% | 0% | $178,978,451 | 5,995,928 | 0 | $29.85 | Q2 2024 | ||
| 31 Mar 2024 | 3% | 0% | $241,036,306 | 5,995,928 | 0 | $40.20 | Q1 2024 | ||
| 31 Dec 2023 | 1.7% | +0.36% | $152,656,327 | 5,995,928 | +1,245,528 | +26% | $25.46 | Q4 2023 | |
| 30 Sep 2023 | 0.38% | +0.03% | $66,030,560 | 4,750,400 | +375,060 | +8.6% | $13.90 | Q3 2023 | |
| 30 Jun 2023 | 0.58% | +0.2% | $100,589,067 | 4,375,340 | +1,495,515 | +52% | $22.99 | Q2 2023 | |
| 31 Mar 2023 | 0.46% | 0% | $85,329,215 | 2,879,825 | 0 | $29.63 | Q1 2023 | ||
| 31 Dec 2022 | 0.43% | 0% | $71,880,432 | 2,879,825 | 0 | $24.96 | Q4 2022 | ||
| 30 Sep 2022 | 0.41% | 0% | $62,694,000 | 2,879,825 | 0 | $21.77 | Q3 2022 | ||
| 30 Jun 2022 | 0.32% | +0.06% | $56,704,000 | 2,879,825 | +495,083 | +21% | $19.69 | Q2 2022 | |
| 31 Mar 2022 | 0.58% | 0% | $100,922,000 | 2,384,742 | 0 | $42.32 | Q1 2022 | ||
| 31 Dec 2021 | 0.74% | 0% | $151,407,000 | 2,384,742 | 0 | $63.49 | Q4 2021 | ||
| 30 Sep 2021 | 0.62% | +0.11% | $140,080,000 | 2,384,742 | +425,531 | +22% | $58.74 | Q3 2021 | |
| 30 Jun 2021 | 0.42% | 0% | $95,022,000 | 1,959,211 | 0 | $48.50 | Q2 2021 | ||
| 31 Mar 2021 | 0.33% | 0% | $76,135,000 | 1,959,211 | 0 | $38.86 | Q1 2021 | ||
| 31 Dec 2020 | 0.46% | 0% | $121,471,000 | 1,959,211 | 0 | $62.00 | Q4 2020 | ||
| 30 Sep 2020 | 0.25% | +0.25% | $63,302,000 | 1,959,211 | +1,959,211 | NEW | $32.31 | Q3 2020 |