uniQure N.V. - Ordinary Shares, par value 0.05 euro (QURE)

CUSIP: N90064101

Q4 2025 13F Holders as of 31 Dec 2025

Type / Class
Equity / Ordinary Shares, par value 0.05 euro
Shares outstanding
63,081,854
Total 13F shares
61,851,729
Share change
+6,308,290
Total reported value
$1,480,102,997
Put/Call ratio
29%
Price per share
$23.93
Number of holders
222
Value change
-$115,090,755
Number of buys
135
Number of sells
124

Security key

N90064101

Report period

Q4 2025

Institutions

222

Top holders

10

Ownership snapshot

Top shareholders of QURE - uniQure N.V. - Ordinary Shares, par value 0.05 euro (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Lead holder
Avoro Capital Advisors LLC
13D/G signal
Avoro Capital Advisors LLC
Evidence rows
50
Latest as of
31 Dec 2025
13F 13D/G Lead comparable stake: 9.9% 13D/G row: Avoro Capital Advisors LLC Showing first 8 of 50 holder rows. Open remaining rows
Holder Evidence Ownership % Position 12M Net Δ As of
Avoro Capital Advisors LLC
13F 13D/G
Company
9.9%
from 13D/G
$259,422,196
4,444,444 shares
30 Sep 2025
SUSQUEHANNA SECURITIES, LLC
13D/G
G1 Execution Services, LLC
5.7%
$82,718,384
3,536,485 shares
$0 31 Dec 2025
Nantahala Capital Management, LLC
13F 13D/G
Company
3.8%
from 13D/G
$58,807,308
1,007,492 shares
30 Sep 2025
Vestal Point Capital, LP
13D/G 13F
Company
0.4%
$13,133,250
225,000 shares
-$202,835,750 30 Sep 2025
FMR LLC
13F
Company
13F
9.6%
$353,697,322
6,059,574 shares
30 Sep 2025
RTW INVESTMENTS, LP
13F
Company
13F
7%
$258,285,382
4,424,968 shares
30 Sep 2025
EcoR1 Capital, LLC
13F
Company
13F
6.3%
$232,836,237
3,988,971 shares
30 Sep 2025
Aberdeen Group plc
13F
Company
13F
4.7%
$171,592,799
2,939,743 shares
30 Sep 2025
Show 42 additional holder rows in the full holder list
Holder Evidence Ownership % Position 12M Net Δ As of
FRANKLIN RESOURCES INC
13F
Company
13F
3.2%
$116,073,446
1,988,581 shares
30 Sep 2025
BlackRock, Inc.
13F
Company
13F
2.3%
$84,408,799
1,446,099 shares
30 Sep 2025
STATE STREET CORP
13F
Company
13F
2.3%
$84,286,864
1,444,010 shares
30 Sep 2025
FRED ALGER MANAGEMENT, LLC
13F
Company
13F
2%
$75,320,123
1,290,391 shares
30 Sep 2025
JPMORGAN CHASE & CO
13F
Company
13F
1.8%
$67,087,617
1,149,351 shares
30 Sep 2025
VANGUARD GROUP INC
13F
Company
13F
1.8%
$65,672,554
1,125,108 shares
30 Sep 2025
683 Capital Management, LLC
13F
Company
13F
1.7%
$62,455,900
1,070,000 shares
30 Sep 2025
JENNISON ASSOCIATES LLC
13F
Company
13F
1.6%
$58,339,880
999,484 shares
30 Sep 2025
PRICE T ROWE ASSOCIATES INC /MD/
13F
Company
13F
1.4%
$53,303,000
913,180 shares
30 Sep 2025
TWO SIGMA INVESTMENTS, LP
13F
Company
13F
1.4%
$52,389,293
897,538 shares
30 Sep 2025
Eversept Partners, LP
13F
Company
13F
1.4%
$51,212,262
877,373 shares
30 Sep 2025
Boxer Capital Management, LLC
13F
Company
13F
1.3%
$46,696,000
800,000 shares
30 Sep 2025
GEODE CAPITAL MANAGEMENT, LLC
13F
Company
13F
1.1%
$42,136,892
721,652 shares
30 Sep 2025
GOLDMAN SACHS GROUP INC
13F
Company
13F
1%
$38,653,081
662,208 shares
30 Sep 2025
Artia Global Partners LP
13F
Company
13F
1%
$38,456,432
658,839 shares
30 Sep 2025
Integral Health Asset Management, LLC
13F
Company
13F
0.95%
$35,022,000
600,000 shares
30 Sep 2025
FARALLON CAPITAL MANAGEMENT LLC
13F
Company
13F
0.9%
$32,979,050
565,000 shares
30 Sep 2025
STEMPOINT CAPITAL LP
13F
Company
13F
0.83%
$30,478,187
522,155 shares
30 Sep 2025
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.
13F
Company
13F
0.83%
$30,450,286
521,677 shares
30 Sep 2025
Deep Track Capital, LP
13F
Company
13F
0.77%
$28,198,080
483,092 shares
30 Sep 2025
ORBIMED ADVISORS LLC
13F
Company
13F
0.73%
$26,762,645
458,500 shares
30 Sep 2025
Caption Management, LLC
13F
Company
13F
0.73%
$26,750,971
458,300 shares
30 Sep 2025
SILVERARC CAPITAL MANAGEMENT, LLC
13F
Company
13F
0.72%
$26,558,350
455,000 shares
30 Sep 2025
CITADEL ADVISORS LLC
13F
Company
13F
0.68%
$25,082,173
429,710 shares
30 Sep 2025
TWO SIGMA ADVISERS, LP
13F
Company
13F
0.65%
$23,902,515
409,500 shares
30 Sep 2025
Darwin Global Management, Ltd.
13F
Company
13F
0.63%
$23,760,000
400,000 shares
30 Sep 2025
Privium Fund Management B.V.
13F
Company
13F
0.61%
$22,530,820
386,000 shares
30 Sep 2025
BNP PARIBAS FINANCIAL MARKETS
13F
Company
13F
0.61%
$22,507,997
385,609 shares
30 Sep 2025
CHARLES SCHWAB INVESTMENT MANAGEMENT INC
13F
Company
13F
0.57%
$20,878,073
357,685 shares
30 Sep 2025
Parkman Healthcare Partners LLC
13F
Company
13F
0.55%
$20,158,430
345,356 shares
30 Sep 2025
BALYASNY ASSET MANAGEMENT L.P.
13F
Company
13F
0.53%
$19,450,927
333,235 shares
30 Sep 2025
MORGAN STANLEY
13F
Company
13F
0.51%
$18,766,013
321,501 shares
30 Sep 2025
Affinity Asset Advisors, LLC
13F
Company
13F
0.48%
$17,511,000
300,000 shares
30 Sep 2025
Logos Global Management LP
13F
Company
13F
0.48%
$17,511,000
300,000 shares
30 Sep 2025
BANK OF AMERICA CORP /DE/
13F
Company
13F
0.47%
$17,226,796
295,131 shares
30 Sep 2025
Catalio Capital Management, LP
13F
Company
13F
0.45%
$16,515,208
282,940 shares
30 Sep 2025
Siren, L.L.C.
13F
Individual
13F
0.44%
$16,063,424
275,200 shares
30 Sep 2025
MACQUARIE GROUP LTD
13F
Company
13F
0.41%
$15,072,000
258,211 shares
30 Sep 2025
Point72 Asset Management, L.P.
13F
Company
13F
0.4%
$14,830,812
254,082 shares
30 Sep 2025
SUSQUEHANNA INTERNATIONAL GROUP, LLP
13F
Company
13F
0.36%
$13,164,770
225,540 shares
30 Sep 2025
ROYAL BANK OF CANADA
13F
Company
13F
0.34%
$12,340,000
211,413 shares
30 Sep 2025
UBS Group AG
13F
Company
13F
0.32%
$11,965,208
204,989 shares
30 Sep 2025
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q4 2025

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions
222
Shares
61,851,729
Rows loaded
222
Investor Option Weight % Change % Reported value * Price Shares Share Change Activity Report Period

* Reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. An asterisk next to the price means the price is likely invalid.

Compare Q4 2025 vs Q3 2025 Across Filers

Q3 2025 holders
218
Q4 2025 holders
222
Holder diff
4
Investor Q3 2025 Shares Q4 2025 Shares Share Diff Share Chg % Q3 2025 value Q4 2025 value Value change Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
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