uniQure N.V. - Ordinary Shares, par value 0.05 euro (QURE)

CUSIP: N90064101

Q4 2025 13F Holders as of 31 Dec 2025

Type / Class
Equity / Ordinary Shares, par value 0.05 euro
Shares outstanding
63,081,854
Total 13F shares
61,851,729
Share change
+6,308,290
Total reported value
$1,480,102,997
Put/Call ratio
29%
Price per share
$23.93
Number of holders
222
Value change
-$115,090,755
Number of buys
135
Number of sells
124

Security key

N90064101

Report period

Q4 2025

Institutions

222

Top holders

10

Top shareholders of QURE - uniQure N.V. - Ordinary Shares, par value 0.05 euro (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Holder Source Role / Reporting Ownership % Shares Holdings Value 12M Net Δ As of Details
Avoro Capital Advisors LLC
13F 13D/G
Company
9.9%
from 13D/G
4,444,444
$259,422,196 30 Sep 2025
SUSQUEHANNA SECURITIES, LLC
13D/G
G1 Execution Services, LLC
5.7%
3,536,485
$82,718,384 $0 31 Dec 2025
Nantahala Capital Management, LLC
13F 13D/G
Company
3.8%
from 13D/G
1,007,492
$58,807,308 30 Sep 2025
Vestal Point Capital, LP
13D/G 13F
Company
0.4%
225,000
$13,133,250 -$202,835,750 30 Sep 2025
FMR LLC
13F
Company
9.6%
6,059,574
$353,697,322 30 Sep 2025
13F
RTW INVESTMENTS, LP
13F
Company
7%
4,424,968
$258,285,382 30 Sep 2025
13F
EcoR1 Capital, LLC
13F
Company
6.3%
3,988,971
$232,836,237 30 Sep 2025
13F
Aberdeen Group plc
13F
Company
4.7%
2,939,743
$171,592,799 30 Sep 2025
13F
FRANKLIN RESOURCES INC
13F
Company
3.2%
1,988,581
$116,073,446 30 Sep 2025
13F
BlackRock, Inc.
13F
Company
2.3%
1,446,099
$84,408,799 30 Sep 2025
13F
STATE STREET CORP
13F
Company
2.3%
1,444,010
$84,286,864 30 Sep 2025
13F
FRED ALGER MANAGEMENT, LLC
13F
Company
2%
1,290,391
$75,320,123 30 Sep 2025
13F
JPMORGAN CHASE & CO
13F
Company
1.8%
1,149,351
$67,087,617 30 Sep 2025
13F
VANGUARD GROUP INC
13F
Company
1.8%
1,125,108
$65,672,554 30 Sep 2025
13F
683 Capital Management, LLC
13F
Company
1.7%
1,070,000
$62,455,900 30 Sep 2025
13F
JENNISON ASSOCIATES LLC
13F
Company
1.6%
999,484
$58,339,880 30 Sep 2025
13F
PRICE T ROWE ASSOCIATES INC /MD/
13F
Company
1.4%
913,180
$53,303,000 30 Sep 2025
13F
TWO SIGMA INVESTMENTS, LP
13F
Company
1.4%
897,538
$52,389,293 30 Sep 2025
13F
Eversept Partners, LP
13F
Company
1.4%
877,373
$51,212,262 30 Sep 2025
13F
Boxer Capital Management, LLC
13F
Company
1.3%
800,000
$46,696,000 30 Sep 2025
13F
GEODE CAPITAL MANAGEMENT, LLC
13F
Company
1.1%
721,652
$42,136,892 30 Sep 2025
13F
GOLDMAN SACHS GROUP INC
13F
Company
1%
662,208
$38,653,081 30 Sep 2025
13F
Artia Global Partners LP
13F
Company
1%
658,839
$38,456,432 30 Sep 2025
13F
Integral Health Asset Management, LLC
13F
Company
0.95%
600,000
$35,022,000 30 Sep 2025
13F
FARALLON CAPITAL MANAGEMENT LLC
13F
Company
0.9%
565,000
$32,979,050 30 Sep 2025
13F
STEMPOINT CAPITAL LP
13F
Company
0.83%
522,155
$30,478,187 30 Sep 2025
13F
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.
13F
Company
0.83%
521,677
$30,450,286 30 Sep 2025
13F
Deep Track Capital, LP
13F
Company
0.77%
483,092
$28,198,080 30 Sep 2025
13F
ORBIMED ADVISORS LLC
13F
Company
0.73%
458,500
$26,762,645 30 Sep 2025
13F
Caption Management, LLC
13F
Company
0.73%
458,300
$26,750,971 30 Sep 2025
13F
SILVERARC CAPITAL MANAGEMENT, LLC
13F
Company
0.72%
455,000
$26,558,350 30 Sep 2025
13F
CITADEL ADVISORS LLC
13F
Company
0.68%
429,710
$25,082,173 30 Sep 2025
13F
TWO SIGMA ADVISERS, LP
13F
Company
0.65%
409,500
$23,902,515 30 Sep 2025
13F
Darwin Global Management, Ltd.
13F
Company
0.63%
400,000
$23,760,000 30 Sep 2025
13F
Privium Fund Management B.V.
13F
Company
0.61%
386,000
$22,530,820 30 Sep 2025
13F
BNP PARIBAS FINANCIAL MARKETS
13F
Company
0.61%
385,609
$22,507,997 30 Sep 2025
13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC
13F
Company
0.57%
357,685
$20,878,073 30 Sep 2025
13F
Parkman Healthcare Partners LLC
13F
Company
0.55%
345,356
$20,158,430 30 Sep 2025
13F
BALYASNY ASSET MANAGEMENT L.P.
13F
Company
0.53%
333,235
$19,450,927 30 Sep 2025
13F
MORGAN STANLEY
13F
Company
0.51%
321,501
$18,766,013 30 Sep 2025
13F
Affinity Asset Advisors, LLC
13F
Company
0.48%
300,000
$17,511,000 30 Sep 2025
13F
Logos Global Management LP
13F
Company
0.48%
300,000
$17,511,000 30 Sep 2025
13F
BANK OF AMERICA CORP /DE/
13F
Company
0.47%
295,131
$17,226,796 30 Sep 2025
13F
Catalio Capital Management, LP
13F
Company
0.45%
282,940
$16,515,208 30 Sep 2025
13F
Siren, L.L.C.
13F
Individual
0.44%
275,200
$16,063,424 30 Sep 2025
13F
MACQUARIE GROUP LTD
13F
Company
0.41%
258,211
$15,072,000 30 Sep 2025
13F
Point72 Asset Management, L.P.
13F
Company
0.4%
254,082
$14,830,812 30 Sep 2025
13F
SUSQUEHANNA INTERNATIONAL GROUP, LLP
13F
Company
0.36%
225,540
$13,164,770 30 Sep 2025
13F
ROYAL BANK OF CANADA
13F
Company
0.34%
211,413
$12,340,000 30 Sep 2025
13F
UBS Group AG
13F
Company
0.32%
204,989
$11,965,208 30 Sep 2025
13F

Institutional Holders of uniQure N.V. - Ordinary Shares, par value 0.05 euro (QURE) as of Q4 2025

As of 31 Dec 2025, uniQure N.V. - Ordinary Shares, par value 0.05 euro (QURE) was held by 222 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 61,851,729 shares. The largest 10 holders included FMR LLC, Avoro Capital Advisors LLC, RTW INVESTMENTS, LP, Aberdeen Group plc, STATE STREET CORP, JPMORGAN CHASE & CO, BlackRock, Inc., TWO SIGMA INVESTMENTS, LP, MPM BIOIMPACT LLC, and JENNISON ASSOCIATES LLC. This page lists 222 institutional shareholders reporting positions in this security for the Q4 2025 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period

Compare Q4 2025 vs Q3 2025 Across Filers

Q3 2025 holders
218
Q4 2025 holders
222
Holder diff
4
Investor Q3 2025 Shares Q4 2025 Shares Share Diff Share Chg % Q3 2025 Value $ Q4 2025 Value $ Value Diff $ Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
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