VYNE Therapeutics Inc. - Common Stock, par value $0.0001 (VYNE)

CUSIP: 92941V308

Q4 2025 13F Holders as of 31 Dec 2025

Type / Class
Equity / Common Stock, par value $0.0001
Shares outstanding
33,333,333
Total 13F shares
8,179,397
Share change
+2,809,841
Total reported value
$4,743,526
Price per share
$0.58
Number of holders
39
Value change
+$1,869,192
Number of buys
19
Number of sells
10

Security key

92941V308

Report period

Q4 2025

Institutions

39

Top holders

10

Top shareholders of VYNE - VYNE Therapeutics Inc. - Common Stock, par value $0.0001 (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Holder Source Role / Reporting Ownership % Shares Holdings Value 12M Net Δ As of Details
CITADEL ADVISORS LLC
13D/G
Kenneth Griffin
0.01%
3,732
$1,250 -$367,360 30 Sep 2025
BAKER BROS. ADVISORS LP
13F
Company
2.6%
851,353
$285,203 30 Sep 2025
13F
ACORN CAPITAL ADVISORS, LLC
13F
Company
1.8%
586,572
$199,434 30 Sep 2025
13F
Shay Capital LLC
13F
Company
1.5%
492,577
$165,013 30 Sep 2025
13F
ACADIAN ASSET MANAGEMENT LLC
13F
Company
1.3%
446,414
$148,000 30 Sep 2025
13F
Ikarian Capital, LLC
13F
Company
0.87%
290,000
$97,149 30 Sep 2025
13F
TWO SIGMA INVESTMENTS, LP
13F
Company
0.66%
220,788
$73,964 30 Sep 2025
13F
VANGUARD GROUP INC
13F
Company
0.57%
190,383
$63,778 30 Sep 2025
13F
JANE STREET GROUP, LLC
13F
Company
0.44%
147,120
$49,285 30 Sep 2025
13F
GEODE CAPITAL MANAGEMENT, LLC
13F
Company
0.41%
137,122
$45,938 30 Sep 2025
13F
BOOTHBAY FUND MANAGEMENT, LLC
13F
Company
0.32%
106,459
$35,664 30 Sep 2025
13F
BRIDGEWAY CAPITAL MANAGEMENT, LLC
13F
Company
0.23%
76,958
$25,781 30 Sep 2025
13F
SUSQUEHANNA INTERNATIONAL GROUP, LLP
13F
Company
0.17%
57,763
$19,351 30 Sep 2025
13F
TWO SIGMA ADVISERS, LP
13F
Company
0.17%
56,600
$18,961 30 Sep 2025
13F
CORSAIR CAPITAL MANAGEMENT, L.P.
13F
Company
0.15%
50,000
$16,750 30 Sep 2025
13F
Rangeley Capital, LLC
13F
Company
0.15%
50,000
$16,750 30 Sep 2025
13F
BlackRock, Inc.
13F
Company
0.13%
44,404
$14,875 30 Sep 2025
13F
GSA CAPITAL PARTNERS LLP
13F
Company
0.11%
35,921
$12,000 30 Sep 2025
13F
NORTHERN TRUST CORP
13F
Company
0.07%
23,110
$7,742 30 Sep 2025
13F
COMMONWEALTH EQUITY SERVICES, LLC
13F
Company
0.05%
18,298
$6,000 30 Sep 2025
13F
STATE STREET CORP
13F
Company
0.05%
15,765
$5,281 30 Sep 2025
13F
Harvest Investment Services, LLC
13F
Company
0.03%
11,059
$3,705 30 Sep 2025
13F
UBS Group AG
13F
Company
0.02%
5,572
$1,866 30 Sep 2025
13F
Tower Research Capital LLC (TRC)
13F
Company
0.01%
3,597
$1,205 30 Sep 2025
13F
ROYAL BANK OF CANADA
13F
Company
0.01%
2,440
$1,000 30 Sep 2025
13F
BANK OF AMERICA CORP /DE/
13F
Company
0%
1,532
$513 30 Sep 2025
13F
MB, LEVIS & ASSOCIATES, LLC
13F
Company
0%
1,041
$349 30 Sep 2025
13F
MORGAN STANLEY
13F
Company
0%
911
$305 30 Sep 2025
13F
JPMORGAN CHASE & CO
13F
Company
0%
146
$49 30 Sep 2025
13F
WELLS FARGO & COMPANY/MN
13F
Company
0%
65
$22 30 Sep 2025
13F
Truvestments Capital LLC
13F
Company
0%
25
$8 30 Sep 2025
13F
Newbridge Financial Services Group, Inc.
13F
Company
0%
10
$3 30 Sep 2025
13F
PERCEPTIVE ADVISORS LLC
3/4/5
10%+ Owner
class O/S missing
4,935,057
$11,251,930 16 Aug 2021
AI Biotechnology LLC
3/4/5
10%+ Owner
class O/S missing
1,116,585
$2,545,814 01 Nov 2023
Andrew Saik
3/4/5
Chief Financial Officer
class O/S missing
116,468
$265,547 28 May 2021
Matthew T. Wiley
3/4/5
Chief Commercial Officer
class O/S missing
109,246
$249,081 30 Jun 2021
Patrick G. Lepore
3/4/5
Director
mixed-class rows
71,472
mixed-class rows
$150,298 12 Dec 2025
STALEY CAPITAL ADVISERS INC
13F
Company
class O/S missing
51,472
$17,243 30 Sep 2025
13F
Fortitude Family Office, LLC
13F
Company
class O/S missing
680
$228 30 Sep 2025
13F
Farther Finance Advisors, LLC
13F
Company
class O/S missing
16
$5 30 Sep 2025
13F
Rex Bright
3/4/5
Director
class O/S missing
20,500
19 Jul 2021
Anthony D. Bruno
3/4/5
Director
class O/S missing
20,000
12 Dec 2024
Christine Borowski
3/4/5
Director
class O/S missing
20,000
12 Dec 2024
Elisabeth Sandoval Little
3/4/5
Director
class O/S missing
20,000
12 Dec 2025
Sharon Barbari
3/4/5
Director
class O/S missing
20,000
12 Dec 2025
Steven L. Basta
3/4/5
Director
class O/S missing
20,000
12 Dec 2025

Institutional Holders of VYNE Therapeutics Inc. - Common Stock, par value $0.0001 (VYNE) as of Q4 2025

As of 31 Dec 2025, VYNE Therapeutics Inc. - Common Stock, par value $0.0001 (VYNE) was held by 39 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 8,179,397 shares. The largest 10 holders included Shay Capital LLC, Anson Funds Management LP, Nantahala Capital Management, LLC, T3 Companies, LLC, ACADIAN ASSET MANAGEMENT LLC, KVP Capital Advisors, LP, VANGUARD GROUP INC, Ikarian Capital, LLC, ADAR1 Capital Management, LLC, and GEODE CAPITAL MANAGEMENT, LLC. This page lists 39 institutional shareholders reporting positions in this security for the Q4 2025 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period

Compare Q4 2025 vs Q3 2025 Across Filers

Q3 2025 holders
31
Q4 2025 holders
39
Holder diff
8
Investor Q3 2025 Shares Q4 2025 Shares Share Diff Share Chg % Q3 2025 Value $ Q4 2025 Value $ Value Diff $ Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
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