TAYSHA GENE THERAPIES, INC. - Common Stock, $0.00001 par value per share (TSHA)

CUSIP: 877619106

Q1 2026 13F Holders as of 31 Mar 2026

Holder snapshot 7 signals
Share change
-3,254,161
Put/Call ratio
25%
SEC-reported price per share
$4.47
Number of holders
187
Value change
-$21,469,003
Number of buys
92
Open additional details 1 more signal available
Number of sells
83
Security identity Names, identifiers, and filing context for this profile. 1 source field
Shares outstanding
332,184,263

Security key

877619106

Report period

Q1 2026

Institutions

187

Top holders

10

Ownership snapshot

Top reported holders of TSHA - TAYSHA GENE THERAPIES, INC. - Common Stock, $0.00001 par value per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
Paul B. Manning
Disclosed value leader
RA CAPITAL MANAGEMENT, L.P.
Comparable rows
15/15
Latest evidence
31 Mar 2026
13D/G 3/4/5 13F Lead comparable stake: 9.8% 13D/G row: Paul B. Manning Showing 1-6 of 15 holder rows.

Quick read

Paul B. Manning leads the comparable SEC ownership view at 9.8%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens Paul B. Manning's linked filing trail.
Comparable ownership Top 5
Paul B. Manning 9.8%
RTW INVESTMENTS, LP 7%
BlackRock, Inc. 6.5%
Vestal Point Capital, LP 6.3%
GOLDMAN SACHS GROUP INC 5.1%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
Paul B. Manning
13D/G 3/4/5
10%+ Owner
9.8%
$59,394,578
25,601,111 shares
$0 30 May 2025
RTW INVESTMENTS, LP
13D/G 13F
Company
7%
$92,480,205
20,689,084 shares
-$12,149,679 31 Mar 2026
BlackRock, Inc.
13F 13D/G
Company
6.5%
from 13D/G
$102,537,212
18,643,129 shares
31 Dec 2025
Vestal Point Capital, LP
13D/G 13F
Company
6.3%
$80,460,000
18,000,000 shares
+$18,997,500 31 Mar 2026
GOLDMAN SACHS GROUP INC
13F 13D/G
Company · THE GOLDMAN SACHS GROUP, INC.
5.1%
from 13D/G
$75,310,065
13,692,739 shares
31 Dec 2025
FMR LLC
13D/G 13F
Company
4.9%
$74,406,012
13,528,366 shares
-$11,547,008 31 Dec 2025
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q1 2026

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions
187
Shares
264,720,110
Rows available
187
Investor Option Weight % Change % SEC-reported value * Price Shares Share Change Activity Report Period

* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q1 2026 vs Q1 2026 Across Filers

Q1 2026 holders
187
Q1 2026 holders
187
Holder diff
0
Investor Q1 2026 Shares Q1 2026 Shares Share Diff Share Chg % Q1 2026 value Q1 2026 value Value change Value Chg %
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