Summit Therapeutics Inc. - COM (SMMT)

CUSIP: 86627T108

Q4 2025 13F Holders as of 31 Dec 2025

Share change
+14,928,945
Put/Call ratio
149%
SEC-reported price per share
$17.49
Number of holders
206
Value change
+$249,329,722
Number of buys
102
Open additional details 1 more signal available
Number of sells
123

Security key

86627T108

Report period

Q4 2025

Institutions

206

Top holders

10

Ownership snapshot

Top reported holders of SMMT - Summit Therapeutics Inc. - COM (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
BAKER BROS. ADVISORS LP
Disclosed value leader
BAKER BROS. ADVISORS LP
Comparable rows
0/15
Latest evidence
30 Sep 2025
13F Highest disclosed value: $696,716,643 15 rows are not safely comparable across share classes. Showing 1-6 of 15 holder rows.

Quick read

BAKER BROS. ADVISORS LP has the largest disclosed position value at $696.72M.

0 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens BAKER BROS. ADVISORS LP's linked filing trail.
Disclosed position value Top 5
BAKER BROS. ADVISORS LP $696.72M
VANGUARD GROUP INC $235.11M
FMR LLC $184.24M
BlackRock, Inc. $152.14M
STATE STREET CORP $131.44M

Value bars compare disclosed positions; verify each figure against the linked filing evidence.

Detailed SEC evidence table Showing 1-6 of 15 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
BAKER BROS. ADVISORS LP
13F
Company
13F
class O/S missing
$696,716,643
33,722,974 shares
30 Sep 2025
VANGUARD GROUP INC
13F
Company
13F
class O/S missing
$235,105,181
11,379,728 shares
30 Sep 2025
FMR LLC
13F
Company
13F
class O/S missing
$184,243,549
8,917,887 shares
30 Sep 2025
BlackRock, Inc.
13F
Company
13F
class O/S missing
$152,135,956
7,363,793 shares
30 Sep 2025
STATE STREET CORP
13F
Company
13F
class O/S missing
$131,437,598
6,361,936 shares
30 Sep 2025
PRICE T ROWE ASSOCIATES INC /MD/
13F
Company
13F
class O/S missing
$93,773,000
4,538,823 shares
30 Sep 2025
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q4 2025

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions
206
Shares
117,788,001
Rows available
206
Investor Option Weight % Change % SEC-reported value * Price Shares Share Change Activity Report Period

* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q4 2025 vs Q3 2025 Across Filers

Q3 2025 holders
230
Q4 2025 holders
206
Holder diff
-24
Investor Q3 2025 Shares Q4 2025 Shares Share Diff Share Chg % Q3 2025 value Q4 2025 value Value change Value Chg %
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