OnKure Therapeutics, Inc. - Common Stock, $0.0001 Par Value (RPHM)

CUSIP: 75974E103

Q4 2025 13F Holders as of 31 Dec 2025

Holder snapshot 3 signals
Share change
0
SEC-reported price per share
$2.90
Number of holders
1
Security identity Names, identifiers, and filing context for this profile. 1 source field
Shares outstanding
41,305,653

Security key

75974E103

Report period

Q4 2025

Institutions

1

Top holders

1

Ownership snapshot

Top reported holders of RPHM - OnKure Therapeutics, Inc. - Common Stock, $0.0001 Par Value (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
ACORN BIOVENTURES, L.P.
Disclosed value leader
ACORN BIOVENTURES, L.P.
Comparable rows
15/15
Latest evidence
24 Nov 2025
3/4/5 13D/G 13F Lead comparable stake: 22% 13D/G row: ACORN BIOVENTURES, L.P. Showing 1-6 of 15 holder rows.

Quick read

ACORN BIOVENTURES, L.P. leads the comparable SEC ownership view at 22%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens ACORN BIOVENTURES, L.P.'s linked filing trail.
Comparable ownership Top 5
ACORN BIOVENTURES, L.P. 22%
Shay Capital LLC 6.3%
Prosight Management, LP 5.8%
CANTOR FITZGERALD & CO. 5.2%
VANGUARD GROUP INC 4.9%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
ACORN BIOVENTURES, L.P.
3/4/5 13D/G
10%+ Owner · Anders Hove
22%
from 13D/G
$9,098,765
4,279,348 shares
mixed-class rows
15 May 2025
Shay Capital LLC
13F 13D/G
Company
6.3%
from 13D/G
$2,524,319
917,934 shares
30 Sep 2025
Prosight Management, LP
13D/G 13F
Company
5.8%
$2,214,578
745,649 shares
$0 24 Nov 2025
CANTOR FITZGERALD & CO.
13D/G
Cantor Fitzgerald Securities
5.2%
$1,606,894
669,539 shares
$0 30 Jun 2025
VANGUARD GROUP INC
13F 13D/G
Company · The Vanguard Group
4.9%
from 13D/G
$1,865,122
678,226 shares
30 Sep 2025
HIGHBRIDGE CAPITAL MANAGEMENT LLC
13F 13D/G
Company
4.2%
from 13D/G
$1,788,100
650,218 shares
30 Sep 2025
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q4 2025

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions
1
Shares
504
Rows available
1
Investor Option Weight % Change % SEC-reported value * Price Shares Share Change Activity Report Period

* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q4 2025 vs Q3 2025 Across Filers

Q3 2025 holders
1
Q4 2025 holders
1
Holder diff
0
Investor Q3 2025 Shares Q4 2025 Shares Share Diff Share Chg % Q3 2025 value Q4 2025 value Value change Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
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