13F reference period
Q2 2026
CUSIP: 71722W107
13F reference period
Q2 2026
Institutions Reporting
160
Shares (Excl. Options)
Price
$10.85
The headline uses the Q2 2026 reference period after its reporting deadline. Available reports may still be incomplete or amended. Newer periods in the history table contain incoming reports and may be incomplete.
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Latest holder context comes from 160 institutions filings for Q2 2026.
Security key
71722W107
13F reference period
Q2 2026
13F holders
160
13D/G owners
5
CIK / CUSIP context first
Broader feeds
Open recent reporting periods for CUSIP 71722W107:
13D/G owners
Large-stake holder rows connected to Schedule 13D/G evidence.
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Frazier Life Sciences Public Fund, L.P. | 8.6% | 0% | $70,447,299 | 5,985,327 | 0% | James N. Topper | 01 Nov 2025 | |
| BlackRock, Inc. | 5.5% | +18% | $47,508,320 | +$12,503,117 | 4,378,647 | +36% | BlackRock, Inc. | 30 Jun 2026 |
| Carlyle Group Inc. | 4.9% | $30,142,485 | 3,496,808 | Carlyle Group Inc. | 28 Aug 2025 | |||
| MILLENNIUM MANAGEMENT LLC | 4.2% | -22% | $36,627,799 | -$8,707,960 | 3,375,834 | -19% | Millennium Management LLC | 30 Jun 2026 |
| PRUDENTIAL FINANCIAL INC | 0% | -100% | $8,705 | -$24,547,397 | 2,630 | -100% | PRUDENTIAL FINANCIAL INC | 31 May 2025 |
13F concentration
Largest 13F positions for this security by reported shares and value.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | 16% | 12,466,489 | 0% | 2.9% | $135,261,406 |
| Medicxi Ventures Management (Jersey) Ltd | 9.4% | 7,464,572 | 0% | 46% | $80,990,606 |
| BlackRock, Inc. | 5.7% | 4,525,129 | +11% | 0% | $49,097,648 |
| Invesco Ltd. | 5.1% | 4,029,731 | -6.8% | 0% | $43,722,581 |
| Carlyle Group Inc. | 4.4% | 3,496,808 | 0% | 0.38% | $37,940,367 |
| MILLENNIUM MANAGEMENT LLC | 4.2% | 3,375,834 | -16% | 0.02% | $36,627,799 |
| VANGUARD CAPITAL MANAGEMENT LLC | 3.3% | 2,656,944 | +2.8% | 0% | $28,827,842 |
| GW&K Investment Management, LLC | 2.7% | 2,166,838 | +52% | 0.18% | $23,510,000 |
| FRANKLIN RESOURCES INC | 2.5% | 1,970,828 | +98% | 0% | $21,383,482 |
| NEA Management Company, LLC | 2.5% | 1,960,169 | 0% | 1.3% | $21,267,834 |
| 683 Capital Management, LLC | 2.3% | 1,850,000 | 0% | 1.8% | $20,072,501 |
| GOLDMAN SACHS GROUP INC | 2.2% | 1,778,032 | +184% | 0% | $19,291,647 |
| STATE STREET CORP | 2% | 1,586,323 | +14% | 0% | $17,211,605 |
| Catalys Pacific, LLC | 1.9% | 1,493,854 | 0% | 7.1% | $16,208,316 |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 1.8% | 1,462,738 | +21% | 0.02% | $15,871,000 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.7% | 1,315,687 | -0.93% | 0% | $14,277,589 |
| WASATCH ADVISORS LP | 1.6% | 1,307,247 | -2.5% | 0.09% | $14,183,630 |
| Ensign Peak Advisors, Inc | 1.3% | 1,051,913 | -35% | 0.02% | $11,413,256 |
| Propel Bio Management, LLC | 1.3% | 1,050,358 | +25% | 6% | $11,396,384 |
| Point72 Asset Management, L.P. | 1.3% | 1,022,193 | 0.02% | $11,090,794 | |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 1% | 796,631 | +20% | 0% | $8,643,446 |
| SummitTX Capital, L.P. | 0.99% | 789,550 | -21% | 0.23% | $8,566,618 |
| HSBC HOLDINGS PLC | 0.89% | 709,695 | 0% | $7,701,936 | |
| MARSHALL WACE, LLP | 0.84% | 666,090 | -23% | 0.01% | $7,227,078 |
| EcoR1 Capital, LLC | 0.79% | 625,000 | 0% | 0.34% | $6,781,250 |
Quarter history
Holder count, reported shares/value, and median price by quarter.
| Period | 13F Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q3 | 3,542,484 | $25,856,249 | +$11,999,270 | $7.30 | 16 |
| 2026 Q2 | 72,073,900 | $782,058,148 | +$34,337,390 | $10.85 | 160 |
| 2026 Q1 | 68,888,502 | $765,464,329 | +$57,584,218 | $11.11 | 173 |
| 2025 Q4 | 61,960,214 | $1,025,500,826 | -$3,898,620 | $16.59 | 173 |
| 2025 Q3 | 62,330,243 | $733,626,032 | +$59,060,064 | $11.77 | 132 |
| 2025 Q2 | 57,415,787 | $550,618,405 | -$26,654,537 | $9.59 | 117 |
| 2025 Q1 | 64,025,009 | $401,391,744 | -$24,944,522 | $6.27 | 136 |
| 2024 Q4 | 66,610,653 | $540,837,976 | -$121,495,122 | $8.12 | 141 |
| 2024 Q3 | 72,636,064 | $1,312,668,227 | +$264,199,549 | $18.08 | 133 |
| 2024 Q2 | 58,109,780 | $598,557,394 | +$27,856,700 | $10.30 | 113 |
| 2024 Q1 | 55,378,949 | $588,085,973 | +$14,631,856 | $10.62 | 112 |
| 2023 Q4 | 54,112,686 | $503,299,407 | +$11,390,968 | $9.13 | 115 |
| 2023 Q3 | 43,760,270 | $452,721,621 | +$5,267,236 | $10.37 | 109 |
| 2023 Q2 | 42,778,866 | $612,591,768 | +$176,400,941 | $14.32 | 103 |
| 2023 Q1 | 30,786,694 | $219,689,484 | +$28,315,357 | $7.14 | 83 |
| 2022 Q4 | 28,212,747 | $316,546,824 | -$21,719,929 | $11.22 | 83 |
| 2022 Q3 | 30,185,827 | $334,342,526 | +$38,042,890 | $11.08 | 87 |
| 2022 Q2 | 27,258,631 | $230,064,222 | +$9,335,400 | $8.44 | 88 |
| 2022 Q1 | 25,654,888 | $349,117,442 | -$176,036,740 | $13.61 | 74 |
| 2021 Q4 | 28,574,214 | $561,954,045 | +$49,942,191 | $19.67 | 82 |
| 2021 Q3 | 25,543,470 | $819,833,454 | +$19,152,056 | $32.10 | 81 |
| 2021 Q2 | 24,918,954 | $843,508,479 | +$13,169,188 | $33.85 | 76 |
| 2021 Q1 | 24,475,818 | $919,193,673 | +$1,760,408 | $37.56 | 82 |
| 2020 Q4 | 24,534,138 | $815,024,391 | +$96,707,884 | $33.22 | 75 |
| 2020 Q3 | 21,632,831 | $793,536,439 | -$7,640,662 | $36.67 | 57 |