Security key
68572M106
Orchestra BioMed Holdings, Inc. - Common Stock, par value $0.0001 per share (OBIO)
CUSIP: 68572M106
Q3 2025 13F Holders as of 30 Sep 2025
- Security type / class
- Equity / Common Stock, par value $0.0001 per share
- Total 13F shares
- 22,434,285
- Total 13F value
- $55,672,466
- Share change
- +4,756,648
- SEC-reported price per share
- $2.48
- Number of holders
- 49
- Value change
- +$11,747,809
- Number of buys
- 24
- Number of sells
- 32
- Shares outstanding
- 62,199,969
Holder snapshot
6 signals
Security identity
Names, identifiers, and filing context for this profile.
1 source field
Report period
Q3 2025
Institutions
49
Top holders
10
OBIO full security history
Ownership snapshot
Full 13F holder table
Orchestra BioMed Holdings, Inc. SEC filings
Orchestra BioMed Holdings, Inc. company facts
Broader feeds
Ownership snapshot
Top reported holders of OBIO - Orchestra BioMed Holdings, Inc. - Common Stock, par value $0.0001 per share (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Comparable stake leader
PERCEPTIVE ADVISORS LLC
Disclosed value leader
RTW INVESTMENTS, LP
Comparable rows
15/15
Latest evidence
01 Aug 2025
3/4/5
13D/G
13F
Lead comparable stake: 10%
13D/G row: PERCEPTIVE ADVISORS LLC
Showing 1-6 of 15 holder rows.
Quick read
PERCEPTIVE ADVISORS LLC leads the comparable SEC ownership view at 10%.
15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Open SEC evidence
Opens PERCEPTIVE ADVISORS LLC's linked filing trail.
Comparable ownership
Top 5
PERCEPTIVE ADVISORS LLC
10%
BlackRock, Inc.
3.7%
RTW INVESTMENTS, LP
13%
VANGUARD GROUP INC
1.9%
Knoll Capital Management, LLC
0.73%
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
Detailed SEC evidence table Showing 1-6 of 15 holder rows
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| PERCEPTIVE ADVISORS LLC |
3/4/5
13D/G
13F
10%+ Owner · Company
|
10%
from 13D/G
|
$18,679,378
6,792,556 shares
mixed-class rows
|
— | 01 Aug 2025 |
| BlackRock, Inc. |
13D/G
13F
Company
|
3.7%
|
$3,619,674
1,430,701 shares
|
$0 | 31 Mar 2025 |
| RTW INVESTMENTS, LP |
13F
Company
|
13%
|
$22,260,246
8,306,062 shares
|
— | 30 Jun 2025 |
| VANGUARD GROUP INC |
13F
Company
|
1.9%
|
$3,101,609
1,157,317 shares
|
— | 30 Jun 2025 |
| Knoll Capital Management, LLC |
13F
Company
|
0.73%
|
$169,824
455,128 shares
|
— | 30 Jun 2025 |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
Company
|
0.7%
|
$1,176,000
438,369 shares
|
— | 30 Jun 2025 |
How to read this table
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
13F holder rows
Institutional holders as of Q3 2025
Investor-level positions for this CUSIP, loaded as an interactive table.
Institutions
49
Shares
22,434,285
Rows available
49
| Investor | Option | Weight % | Change % | SEC-reported value | * Price | Shares | Share Change | Activity | Report Period |
|---|
* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.
Compare Q3 2025 vs Q2 2025 Across Filers
Q2 2025 holders
57
Q3 2025 holders
49
Holder diff
-8
| Investor | Q2 2025 Shares | Q3 2025 Shares | Share Diff | Share Chg % | Q2 2025 value | Q3 2025 value | Value change | Value Chg % |
|---|