What does CUSIP 68375N103 represent in this 13F holders report?

CUSIP 68375N103 is the security identifier for OPK - OPKO HEALTH, INC. - Common Stock, par value $0.01 per share used to aggregate holder disclosures.

How many institutions held OPK - OPKO HEALTH, INC. - Common Stock, par value $0.01 per share in Q4 2021?

222 institutional investors reported OPK - OPKO HEALTH, INC. - Common Stock, par value $0.01 per share for Q4 2021. Use the holders table for investor-level position and value details.

OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (OPK)

CUSIP: 68375N103

Q4 2021 13F Holders as of 31 Dec 2021

Security type / class: Equity / Common Stock, par value $0.01 per share
Total 13F shares: 190,116,095
Total 13F value: $914,661,536
Share change: +6,402,478
Put/Call ratio: 83%
SEC-reported price per share: $4.81
Number of holders: 222
Value change: +$32,672,752
Number of buys: 93
Number of sells: 82
Shares outstanding: 749,059,842

Security key

68375N103

Report period

Q4 2021

Institutions

222

Top holders

OPK full security history Ownership snapshot Full 13F holder table Newer quarter: Q3 2026 OPKO HEALTH, INC. SEC filings OPKO HEALTH, INC. company facts OPKO HEALTH, INC. 13D/G history

Broader feeds

Latest 13F filings Latest 13D/G filings Investors directory

Reporting periods

Holder history for CUSIP 68375N103

Newer quarter: Q3 2026

Recent filing periods:

Q3 2026

Ownership snapshot

Top reported holders of OPK - OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader

VANGUARD GROUP INC

Disclosed value leader

VANGUARD GROUP INC

Comparable rows

0/15

Latest evidence

30 Sep 2021

13F Highest disclosed value: $129,450,000 15 rows are not safely comparable across share classes. Showing 1-6 of 15 holder rows.

Quick read

VANGUARD GROUP INC has the largest disclosed position value at $129.45M.

0 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens VANGUARD GROUP INC's linked filing trail.

Disclosed position value Top 5

VANGUARD GROUP INC $129.45M

BlackRock Finance, Inc. $127.12M

STATE STREET CORP $85.32M

ORACLE INVESTMENT MANAGEMENT INC $46.79M

GEODE CAPITAL MANAGEMENT, LLC $28.21M

Value bars compare disclosed positions; verify each figure against the linked filing evidence.

Detailed SEC evidence table Showing 1-6 of 15 holder rows

Holder	Evidence	Ownership %	Position	12M Net Δ	As of
VANGUARD GROUP INC	13F Company 13F	— denominator unverified	$129,450,000 35,465,884 shares	—	30 Sep 2021
BlackRock Finance, Inc.	13F Company 13F	— denominator unverified	$127,115,000 34,825,680 shares	—	30 Sep 2021
STATE STREET CORP	13F Company 13F	— denominator unverified	$85,317,000 23,374,615 shares	—	30 Sep 2021
ORACLE INVESTMENT MANAGEMENT INC	13F Company 13F	— denominator unverified	$46,790,000 12,819,073 shares	—	30 Sep 2021
GEODE CAPITAL MANAGEMENT, LLC	13F Company 13F	— denominator unverified	$28,209,000 7,728,730 shares	—	30 Sep 2021
NORTHERN TRUST CORP	13F Company 13F	— denominator unverified	$23,038,000 6,311,950 shares	—	30 Sep 2021

How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q4 2021

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions

222

190,116,095

Rows available

222

Investor	Option	Weight %	Change %	SEC-reported value	* Price	Shares	Share Change	Activity	Report Period

^* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q4 2021 vs Q3 2021 Across Filers

Q3 2021 holders

196

Q4 2021 holders

222

Holder diff

Investor	Q3 2021 Shares	Q4 2021 Shares	Share Diff	Share Chg %	Q3 2021 value	Q4 2021 value	Value change	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend