Security key
50015M109
CUSIP: 50015M109
Security key
50015M109
Report period
Q4 2025
Institutions
158
Top holders
10
Broader feeds
Reporting periods
Recent filing periods:
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP |
3/4/5
13D/G
13F
|
Director, 10%+ Owner · Company |
33%
from 13D/G
|
18,398,772
mixed-class rows
|
$422,251,756 | +$60,000,008 | 18 Dec 2025 | |
| Victor Perlroth |
13D/G
|
D. VICTOR PERLROTH, M.D. |
9.9%
|
6,504,427
|
$176,074,839 | +$9,203,800 | 31 Dec 2025 | |
| BlackRock, Inc. |
13F
|
Company |
4.8%
|
2,952,381
|
$48,330,476 | — | 30 Sep 2025 | |
| Point72 Asset Management, L.P. |
13F
|
Company |
4.6%
|
2,837,116
|
$46,443,593 | — | 30 Sep 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
3.2%
|
1,950,292
|
$31,926,280 | — | 30 Sep 2025 | |
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
13F
|
Company |
2.2%
|
1,335,000
|
$21,853,950 | — | 30 Sep 2025 | |
| ICONIQ Capital, LLC |
13F
|
Company |
2.1%
|
1,266,563
|
$20,733,636 | — | 30 Sep 2025 | |
| TCG Crossover Management, LLC |
13F
|
Company |
1.9%
|
1,145,538
|
$18,752,457 | — | 30 Sep 2025 | |
| SILVERARC CAPITAL MANAGEMENT, LLC |
13F
|
Company |
1.6%
|
1,000,000
|
$16,370,000 | — | 30 Sep 2025 | |
| ACADIAN ASSET MANAGEMENT LLC |
13F
|
Company |
1.6%
|
969,906
|
$15,874,000 | — | 30 Sep 2025 | |
| STATE STREET CORP |
13F
|
Company |
1.4%
|
832,443
|
$13,627,092 | — | 30 Sep 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
1.3%
|
801,440
|
$13,121,912 | — | 30 Sep 2025 | |
| Boxer Capital Management, LLC |
13F
|
Company |
1.2%
|
750,000
|
$12,277,500 | — | 30 Sep 2025 | |
| BOONE CAPITAL MANAGEMENT LLC |
13F
|
Company |
1.2%
|
715,877
|
$11,718,906 | — | 30 Sep 2025 | |
| Board of Trustees of The Leland Stanford Junior University |
13F
|
Company |
1.1%
|
691,767
|
$11,324,226 | — | 30 Sep 2025 | |
| MORGAN STANLEY |
13F
|
Company |
1.1%
|
647,587
|
$10,600,998 | — | 30 Sep 2025 | |
| PERCEPTIVE ADVISORS LLC |
13F
|
Company |
1%
|
634,577
|
$10,388,025 | — | 30 Sep 2025 | |
| DIMENSIONAL FUND ADVISORS LP |
13F
|
Company |
0.84%
|
518,000
|
$8,477,714 | — | 30 Sep 2025 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
0.82%
|
502,222
|
$8,222,000 | — | 30 Sep 2025 | |
| RENAISSANCE TECHNOLOGIES LLC |
13F
|
Company |
0.75%
|
461,300
|
$7,551,481 | — | 30 Sep 2025 | |
| D. E. Shaw & Co., Inc. |
13F
|
Company |
0.75%
|
457,856
|
$7,495,103 | — | 30 Sep 2025 | |
| Ikarian Capital, LLC |
13F
|
Company |
0.67%
|
413,841
|
$6,774,577 | — | 30 Sep 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.55%
|
337,904
|
$5,531,489 | — | 30 Sep 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
0.53%
|
326,776
|
$5,349,323 | — | 30 Sep 2025 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
0.5%
|
309,071
|
$5,059,492 | — | 30 Sep 2025 | |
| Nantahala Capital Management, LLC |
13F
|
Company |
0.47%
|
290,884
|
$4,761,771 | — | 30 Sep 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.46%
|
279,481
|
$4,575,104 | — | 30 Sep 2025 | |
| Bruce & Co., Inc. |
13F
|
Company |
0.46%
|
279,308
|
$4,572,272 | — | 30 Sep 2025 | |
| FMR LLC |
13F
|
Company |
0.43%
|
263,053
|
$4,306,177 | — | 30 Sep 2025 | |
| Vestal Point Capital, LP |
13F
|
Company |
0.41%
|
250,000
|
$4,092,500 | — | 30 Sep 2025 | |
| FEDERATED HERMES, INC. |
13F
|
Company |
0.4%
|
244,231
|
$3,998,061 | — | 30 Sep 2025 | |
| TWO SIGMA ADVISERS, LP |
13F
|
Company |
0.34%
|
209,400
|
$3,427,878 | — | 30 Sep 2025 | |
| ROYAL BANK OF CANADA |
13F
|
Company |
0.33%
|
200,894
|
$3,289,000 | — | 30 Sep 2025 | |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
13F
|
Company |
0.28%
|
171,404
|
$2,805,883 | — | 30 Sep 2025 | |
| RIA Advisory Group LLC |
13F
|
Company |
0.27%
|
165,534
|
$2,709,792 | — | 30 Sep 2025 | |
| JACOBS LEVY EQUITY MANAGEMENT, INC |
13F
|
Company |
0.27%
|
165,220
|
$2,704,651 | — | 30 Sep 2025 | |
| MILLENNIUM MANAGEMENT LLC |
13F
|
Company |
0.25%
|
155,255
|
$2,541,524 | — | 30 Sep 2025 | |
| PANAGORA ASSET MANAGEMENT INC |
13F
|
Company |
0.25%
|
154,905
|
$2,535,795 | — | 30 Sep 2025 | |
| FRED ALGER MANAGEMENT, LLC |
13F
|
Company |
0.23%
|
138,303
|
$2,264,020 | — | 30 Sep 2025 | |
| TWO SIGMA INVESTMENTS, LP |
13F
|
Company |
0.23%
|
138,261
|
$2,263,333 | — | 30 Sep 2025 | |
| JANE STREET GROUP, LLC |
13F
|
Company |
0.21%
|
126,613
|
$2,072,655 | — | 30 Sep 2025 | |
| Nuveen, LLC |
13F
|
Company |
0.2%
|
121,412
|
$1,987,515 | — | 30 Sep 2025 | |
| WELLINGTON MANAGEMENT GROUP LLP |
13F
|
Company |
0.19%
|
117,059
|
$1,916,257 | — | 30 Sep 2025 | |
| BOOTHBAY FUND MANAGEMENT, LLC |
13F
|
Company |
0.19%
|
116,435
|
$1,906,041 | — | 30 Sep 2025 | |
| Bank of New York Mellon Corp |
13F
|
Company |
0.17%
|
104,453
|
$1,709,896 | — | 30 Sep 2025 | |
| Invesco Ltd. |
13F
|
Company |
0.16%
|
100,179
|
$1,639,930 | — | 30 Sep 2025 | |
| TANG CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.16%
|
100,000
|
$1,637,000 | — | 30 Sep 2025 | |
| GSA CAPITAL PARTNERS LLP |
13F
|
Company |
0.14%
|
87,697
|
$1,436,000 | — | 30 Sep 2025 | |
| AMERICAN CENTURY COMPANIES INC |
13F
|
Company |
0.13%
|
78,178
|
$1,279,774 | — | 30 Sep 2025 | |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC |
13F
|
Company |
0.12%
|
72,200
|
$1,181,914 | — | 30 Sep 2025 |
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
| Investor | Q3 2025 Shares | Q4 2025 Shares | Share Diff | Share Chg % | Q3 2025 Value $ | Q4 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).