13F reference period
Q2 2026
CUSIP: 50015M109
13F reference period
Q2 2026
Institutions Reporting
199
Shares (Excl. Options)
Price
$38.96
The headline uses the Q2 2026 reference period after its reporting deadline. Available reports may still be incomplete or amended. Newer periods in the history table contain incoming reports and may be incomplete.
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Latest holder context comes from 199 institutions filings for Q2 2026.
Security key
50015M109
13F reference period
Q2 2026
13F holders
199
13D/G owners
6
CIK / CUSIP context first
Broader feeds
Open recent reporting periods for CUSIP 50015M109:
13D/G owners
Large-stake holder rows connected to Schedule 13D/G evidence.
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | 35% | +6.7% | $823,541,243 | +$74,018,549 | 22,049,297 | +9.9% | Baker Bros. Advisors LP | 28 Sep 2026 |
| PERLROTH VICTOR | 9.9% | -10% | $176,074,839 | +$9,203,800 | 6,504,427 | +5.5% | D. VICTOR PERLROTH, M.D. | 31 Dec 2025 |
| Sirenia Capital Management LP | 5.7% | $146,615,250 | 3,495,000 | Sirenia Capital Management LP | 31 Mar 2026 | |||
| BlackRock, Inc. | 5.3% | +22% | $124,781,474 | +$37,029,577 | 3,273,386 | +42% | BlackRock, Inc. | 31 Mar 2026 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 5.2% | $125,201,468 | 3,248,611 | T. Rowe Price Associates, Inc. | 30 Jun 2026 | |||
| Point72 Asset Management, L.P. | 1% | -62% | $15,342,719 | -$39,177,215 | 609,806 | -72% | POINT72 ASSET MANAGEMENT, L.P. | 26 Mar 2026 |
13F concentration
Largest 13F positions for this security by reported shares and value.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | 32% | 19,919,186 | 0% | 3.9% | $776,051,487 |
| BlackRock, Inc. | 6.6% | 4,135,355 | +5.1% | 0% | $161,113,431 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 5.2% | 3,248,611 | +59% | 0.01% | $126,567,000 |
| STATE STREET CORP | 3.8% | 2,419,417 | +7.5% | 0% | $94,260,486 |
| GOLDMAN SACHS GROUP INC | 3.7% | 2,316,014 | +37% | 0.01% | $90,231,905 |
| VANGUARD CAPITAL MANAGEMENT LLC | 2.9% | 1,804,632 | +5.1% | 0% | $70,308,463 |
| BRAIDWELL LP | 2.8% | 1,787,318 | -1.7% | 2.6% | $69,633,909 |
| Jupiter Topco LLC | 2.4% | 1,526,006 | 0% | 0.02% | $59,506,604 |
| RTW INVESTMENTS, LP | 2.4% | 1,487,934 | 0% | 0.49% | $57,969,909 |
| Boxer Capital Management, LLC | 2.3% | 1,477,600 | +8.6% | 4.3% | $57,567,296 |
| T. Rowe Price Investment Management, Inc. | 2.3% | 1,477,033 | +76% | 0.04% | $57,546,000 |
| TCG Crossover Management, LLC | 2.3% | 1,445,538 | 0% | 1.4% | $56,318,161 |
| ICONIQ Capital, LLC | 2% | 1,266,563 | 0% | 1.4% | $49,345,294 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.7% | 1,062,955 | +6.3% | 0% | $41,420,974 |
| Ikarian Capital, LLC | 1.7% | 1,059,730 | -16% | 6.8% | $41,287,080 |
| Artisan Partners Limited Partnership | 1.5% | 968,037 | +40% | 0.06% | $37,714,722 |
| WELLINGTON MANAGEMENT GROUP LLP | 1.3% | 793,613 | +82% | 0.01% | $30,919,164 |
| Board of Trustees of The Leland Stanford Junior University | 1.1% | 691,767 | 0% | 5.1% | $26,951,242 |
| SILVERARC CAPITAL MANAGEMENT, LLC | 0.87% | 546,256 | -45% | 2.4% | $21,282,134 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 0.85% | 532,819 | +46% | 0% | $20,758,628 |
| Squadron Capital Management LLC | 0.79% | 500,000 | +32% | 6.7% | $19,480,000 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 0.79% | 500,000 | -13% | 0.03% | $19,480,000 |
| TWO SIGMA INVESTMENTS, LP | 0.75% | 473,001 | +376% | 0.01% | $18,428,119 |
| MORGAN STANLEY | 0.69% | 435,029 | -16% | 0% | $16,948,748 |
| BANK OF AMERICA CORP /DE/ | 0.61% | 383,709 | +28% | 0% | $14,949,303 |
Quarter history
Holder count, reported shares/value, and median price by quarter.
| Period | 13F Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q3 | 163,569 | $15,506,216 | +$1,993,128 | $94.80 | 22 |
| 2026 Q2 | 60,475,186 | $2,356,009,646 | +$90,264,522 | $38.96 | 199 |
| 2026 Q1 | 57,975,518 | $2,209,267,977 | +$29,590,745 | $38.12 | 187 |
| 2025 Q4 | 57,572,794 | $1,609,734,792 | +$370,103,419 | $27.96 | 158 |
| 2025 Q3 | 44,409,062 | $726,959,997 | +$47,093,150 | $16.37 | 119 |
| 2025 Q2 | 41,677,040 | $155,449,557 | -$3,948,804 | $3.73 | 97 |
| 2025 Q1 | 42,863,422 | $120,238,274 | -$1,691,305 | $2.80 | 105 |
| 2024 Q4 | 42,025,210 | $418,150,232 | +$28,399,955 | $9.95 | 103 |
| 2024 Q3 | 39,359,164 | $102,722,357 | -$2,021,821 | $2.61 | 93 |
| 2024 Q2 | 40,056,656 | $94,129,306 | -$14,468,016 | $2.35 | 101 |
| 2024 Q1 | 43,283,972 | $227,679,928 | +$15,068,792 | $5.26 | 108 |
| 2023 Q4 | 40,982,628 | $124,585,412 | -$3,054,862 | $3.04 | 94 |
| 2023 Q3 | 42,510,554 | $76,519,254 | -$23,940,227 | $1.80 | 99 |
| 2023 Q2 | 42,288,664 | $291,744,523 | +$9,106,566 | $6.90 | 124 |
| 2023 Q1 | 41,098,691 | $254,805,740 | -$6,309,283 | $6.20 | 125 |
| 2022 Q4 | 41,952,613 | $300,395,453 | -$9,903,759 | $7.16 | 132 |
| 2022 Q3 | 41,990,657 | $324,980,600 | +$9,499,406 | $7.74 | 131 |
| 2022 Q2 | 40,950,105 | $313,079,219 | -$7,672,170 | $7.64 | 123 |
| 2022 Q1 | 42,158,020 | $325,458,081 | -$254,071,313 | $7.72 | 128 |
| 2021 Q4 | 45,079,072 | $3,822,215,184 | -$36,808,189 | $84.78 | 145 |
| 2021 Q3 | 45,493,926 | $4,367,284,562 | +$50,836,943 | $95.98 | 147 |
| 2021 Q2 | 44,985,327 | $4,182,158,598 | +$73,153,172 | $93.00 | 146 |
| 2021 Q1 | 44,048,719 | $4,993,605,682 | +$13,960,869 | $113.39 | 161 |
| 2020 Q4 | 44,114,751 | $6,480,914,759 | +$1,024,002,515 | $146.91 | 175 |
| 2020 Q3 | 37,341,540 | $2,211,040,130 | -$82,023,480 | $59.21 | 137 |