Security key
48576U106
Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI)
CUSIP: 48576U106
Q4 2022 13F Holders as of 31 Dec 2022
- Type / Class
- Equity / Common Stock, par value $0.0001 per share
- Shares outstanding
- 22,658,403
- Total 13F shares
- 98,414,676
- Share change
- +31,404,143
- Total reported value
- $334,456,268
- Put/Call ratio
- 140%
- Price per share
- $3.40
- Number of holders
- 152
- Value change
- +$99,576,581
- Number of buys
- 89
- Number of sells
- 60
Report period
Q4 2022
Institutions
152
Top holders
10
KPTI full security history
Newer quarter: Q1 2023
Previous quarter: Q3 2022
Karyopharm Therapeutics Inc. SEC filings
Karyopharm Therapeutics Inc. company facts
Broader feeds
Reporting periods
Holder history for CUSIP 48576U106
Recent filing periods:
Top shareholders of KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| STATE STREET CORP |
13F
|
Company |
40%
|
9,010,339
|
$49,196,000 | — | 30 Sep 2022 | |
| BlackRock Finance, Inc. |
13F
|
Company |
35%
|
7,912,954
|
$43,203,000 | — | 30 Sep 2022 | |
| Palo Alto Investors LP |
13F
|
Company |
25%
|
5,621,533
|
$30,694,000 | — | 30 Sep 2022 | |
| VANGUARD GROUP INC |
13F
|
Company |
21%
|
4,813,399
|
$26,282,000 | — | 30 Sep 2022 | |
| Rubric Capital Management LP |
13F
|
Company |
18%
|
3,990,126
|
$21,786,000 | — | 30 Sep 2022 | |
| Nuveen Asset Management, LLC |
13F
|
Company |
8.7%
|
1,971,048
|
$10,762,000 | — | 30 Sep 2022 | |
| Commodore Capital LP |
13F
|
Company |
8.5%
|
1,935,609
|
$10,568,000 | — | 30 Sep 2022 | |
| CITADEL ADVISORS LLC |
13F
|
Company |
8%
|
1,809,646
|
$9,881,000 | — | 30 Sep 2022 | |
| JACOBS LEVY EQUITY MANAGEMENT, INC |
13F
|
Company |
7%
|
1,582,524
|
$8,641,000 | — | 30 Sep 2022 | |
| Ally Bridge Group (NY) LLC |
13F
|
Company |
6.7%
|
1,528,580
|
$8,346,000 | — | 30 Sep 2022 | |
| Woodline Partners LP |
13F
|
Company |
6.7%
|
1,513,259
|
$8,262,000 | — | 30 Sep 2022 | |
| C WorldWide Group Holding A/S |
13F
|
Company |
6.6%
|
1,500,000
|
$8,190,000 | — | 30 Sep 2022 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
6%
|
1,355,176
|
$7,399,000 | — | 30 Sep 2022 | |
| S.c.a. Candriam |
13F
|
Individual |
5.9%
|
1,335,026
|
$7,290,000 | — | 30 Sep 2022 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
5.9%
|
1,330,435
|
$7,264,000 | — | 30 Sep 2022 | |
| MORGAN STANLEY |
13F
|
Company |
4.8%
|
1,079,851
|
$5,896,000 | — | 30 Sep 2022 | |
| RICE HALL JAMES & ASSOCIATES, LLC |
13F
|
Company |
4%
|
909,083
|
$4,964,000 | — | 30 Sep 2022 | |
| ACADIAN ASSET MANAGEMENT LLC |
13F
|
Company |
3.8%
|
850,576
|
$4,643,000 | — | 30 Sep 2022 | |
| TWO SIGMA ADVISERS, LP |
13F
|
Company |
3.7%
|
831,300
|
$4,539,000 | — | 30 Sep 2022 | |
| BNP PARIBAS FINANCIAL MARKETS |
13F
|
Company |
3.4%
|
762,520
|
$4,163,359 | — | 30 Sep 2022 | |
| NORTHERN TRUST CORP |
13F
|
Company |
3.3%
|
753,779
|
$4,116,000 | — | 30 Sep 2022 | |
| Altium Capital Management LLC |
13F
|
Company |
3.3%
|
750,000
|
$4,095,000 | — | 30 Sep 2022 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
3.2%
|
731,861
|
$3,996,000 | — | 30 Sep 2022 | |
| ExodusPoint Capital Management, LP |
13F
|
Company |
3.1%
|
707,280
|
$3,862,000 | — | 30 Sep 2022 | |
| Walleye Capital LLC |
13F
|
Company |
3%
|
673,672
|
$3,678,000 | — | 30 Sep 2022 | |
| Rafferty Asset Management, LLC |
13F
|
Company |
2.9%
|
668,004
|
$3,647,000 | — | 30 Sep 2022 | |
| FRONTIER CAPITAL MANAGEMENT CO LLC |
13F
|
Company |
2.8%
|
629,154
|
$3,435,000 | — | 30 Sep 2022 | |
| CITIGROUP INC |
13F
|
Company |
2.7%
|
607,396
|
$3,316,000 | — | 30 Sep 2022 | |
| BALYASNY ASSET MANAGEMENT L.P. |
13F
|
Company |
2.6%
|
595,558
|
$3,252,000 | — | 30 Sep 2022 | |
| DEUTSCHE BANK AG\ |
13F
|
Company |
2.6%
|
593,817
|
$3,242,000 | — | 30 Sep 2022 | |
| Lombard Odier Asset Management (Switzerland) SA |
13F
|
Company |
2.1%
|
479,124
|
$2,616,000 | — | 30 Sep 2022 | |
| BARCLAYS PLC |
13F
|
Company |
2%
|
455,464
|
$2,487,000 | — | 30 Sep 2022 | |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
13F
|
Company |
1.7%
|
391,917
|
$2,139,000 | — | 30 Sep 2022 | |
| MACQUARIE GROUP LTD |
13F
|
Company |
1.7%
|
381,465
|
$2,086,000 | — | 30 Sep 2022 | |
| RENAISSANCE TECHNOLOGIES LLC |
13F
|
Company |
1.4%
|
308,300
|
$1,683,000 | — | 30 Sep 2022 | |
| Bank of New York Mellon Corp |
13F
|
Company |
1.3%
|
298,991
|
$1,632,000 | — | 30 Sep 2022 | |
| Hennion & Walsh Asset Management, Inc. |
13F
|
Company |
1.2%
|
276,422
|
$1,509,000 | — | 30 Sep 2022 | |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) |
13F
|
Company |
1.2%
|
271,219
|
$1,481,000 | — | 30 Sep 2022 | |
| Birchview Capital, LP |
13F
|
Company |
1.2%
|
269,332
|
$1,471,000 | — | 30 Sep 2022 | |
| MILLENNIUM MANAGEMENT LLC |
13F
|
Company |
1.2%
|
262,686
|
$1,434,000 | — | 30 Sep 2022 | |
| WELLINGTON MANAGEMENT GROUP LLP |
13F
|
Company |
1.1%
|
245,134
|
$1,338,000 | — | 30 Sep 2022 | |
| TWO SIGMA INVESTMENTS, LP |
13F
|
Company |
1%
|
228,335
|
$1,247,000 | — | 30 Sep 2022 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.88%
|
200,501
|
$1,095,000 | — | 30 Sep 2022 | |
| JPMORGAN CHASE & CO |
13F
|
Company |
0.79%
|
179,227
|
$978,000 | — | 30 Sep 2022 | |
| VOYA INVESTMENT MANAGEMENT LLC |
13F
|
Company |
0.76%
|
171,621
|
$937,050 | — | 30 Sep 2022 | |
| AMERIPRISE FINANCIAL INC |
13F
|
Company |
0.75%
|
170,029
|
$929,000 | — | 30 Sep 2022 | |
| Swiss National Bank |
13F
|
Company |
0.75%
|
169,450
|
$925,000 | — | 30 Sep 2022 | |
| MARSHALL WACE, LLP |
13F
|
Company |
0.7%
|
159,137
|
$868,000 | — | 30 Sep 2022 | |
| Connor, Clark & Lunn Investment Management Ltd. |
13F
|
Company |
0.69%
|
155,433
|
$849,000 | — | 30 Sep 2022 | |
| D. E. Shaw & Co., Inc. |
13F
|
Company |
0.63%
|
143,806
|
$785,000 | — | 30 Sep 2022 |
Institutional Holders of Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI) as of Q4 2022
As of 31 Dec 2022,
Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI) was held by
152 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
98,414,676 shares.
The largest 10 holders included
Avidity Partners Management LP, BlackRock Inc., Rubric Capital Management LP, STATE STREET CORP, Palo Alto Investors LP, VANGUARD GROUP INC, ARMISTICE CAPITAL, LLC, CITADEL ADVISORS LLC, JACOBS LEVY EQUITY MANAGEMENT, INC, and MARSHALL WACE, LLP.
This page lists
152
institutional shareholders reporting positions in this security
for the Q4 2022 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q4 2022 vs Q3 2022 Across Filers
Q3 2022 holders
142
Q4 2022 holders
152
Holder diff
10
| Investor | Q3 2022 Shares | Q4 2022 Shares | Share Diff | Share Chg % | Q3 2022 Value $ | Q4 2022 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.