Security key
48576U106
Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI)
CUSIP: 48576U106
Q4 2020 13F Holders as of 31 Dec 2020
- Security type / class
- Equity / Common Stock, par value $0.0001 per share
- Total 13F shares
- 63,829,194
- Total 13F value
- $988,058,899
- Share change
- -3,915,618
- Put/Call ratio
- 70%
- SEC-reported price per share
- $15.48
- Number of holders
- 165
- Value change
- -$54,468,075
- Number of buys
- 82
- Number of sells
- 64
- Shares outstanding
- 22,658,403
Holder snapshot
7 signals
Open additional details 1 more signal available
Security identity
Names, identifiers, and filing context for this profile.
1 source field
Report period
Q4 2020
Institutions
165
Top holders
10
KPTI full security history
Ownership snapshot
Full 13F holder table
Newer quarter: Q3 2025
Karyopharm Therapeutics Inc. SEC filings
Karyopharm Therapeutics Inc. company facts
Broader feeds
Reporting periods
Holder history for CUSIP 48576U106
Recent filing periods:
Ownership snapshot
Top reported holders of KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Comparable stake leader
BlackRock Finance, Inc.
Disclosed value leader
BlackRock Finance, Inc.
Comparable rows
15/15
Latest evidence
30 Sep 2020
13F
Lead comparable stake: 32%
Showing 1-6 of 15 holder rows.
Quick read
BlackRock Finance, Inc. leads the comparable SEC ownership view at 32%.
15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Open SEC evidence
Opens BlackRock Finance, Inc.'s linked filing trail.
Comparable ownership
Top 5
BlackRock Finance, Inc.
32%
Avoro Capital Advisors LLC
26%
Palo Alto Investors LP
22%
STATE STREET CORP
21%
FRONTIER CAPITAL MANAGEMENT CO LLC
16%
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
Detailed SEC evidence table Showing 1-6 of 15 holder rows
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| BlackRock Finance, Inc. |
13F
Company
|
32%
|
$104,679,000
7,169,789 shares
|
— | 30 Sep 2020 |
| Avoro Capital Advisors LLC |
13F
Company
|
26%
|
$87,600,000
6,000,000 shares
|
— | 30 Sep 2020 |
| Palo Alto Investors LP |
13F
Company
|
22%
|
$74,258,000
5,086,152 shares
|
— | 30 Sep 2020 |
| STATE STREET CORP |
13F
Company
|
21%
|
$69,919,000
4,788,974 shares
|
— | 30 Sep 2020 |
| FRONTIER CAPITAL MANAGEMENT CO LLC |
13F
Company
|
16%
|
$54,075,000
3,703,786 shares
|
— | 30 Sep 2020 |
| VANGUARD GROUP INC |
13F
Company
|
15%
|
$50,284,000
3,444,065 shares
|
— | 30 Sep 2020 |
How to read this table
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
13F holder rows
Institutional holders as of Q4 2020
Investor-level positions for this CUSIP, loaded as an interactive table.
Institutions
165
Shares
63,829,194
Rows available
165
| Investor | Option | Weight % | Change % | SEC-reported value | * Price | Shares | Share Change | Activity | Report Period |
|---|
* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.
Compare Q4 2020 vs Q4 2025 Across Filers
Q4 2025 holders
0
Q4 2020 holders
165
Holder diff
165
| Investor | Q4 2025 Shares | Q4 2020 Shares | Share Diff | Share Chg % | Q4 2025 value | Q4 2020 value | Value change | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend