Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI)

CUSIP: 48576U106

Q4 2020 13F Holders as of 31 Dec 2020

Type / Class
Equity / Common Stock, par value $0.0001 per share
Shares outstanding
22,658,403
Total 13F shares
63,829,194
Share change
-3,915,618
Total reported value
$988,058,899
Put/Call ratio
70%
Price per share
$15.48
Number of holders
165
Value change
-$54,468,075
Number of buys
82
Number of sells
64

Security key

48576U106

Report period

Q4 2020

Institutions

165

Top holders

10

Top shareholders of KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Holder Source Role / Reporting Ownership % Shares Holdings Value 12M Net Δ As of Details
BlackRock Finance, Inc.
13F
Company
32%
7,169,789
$104,679,000 30 Sep 2020
13F
Avoro Capital Advisors LLC
13F
Company
26%
6,000,000
$87,600,000 30 Sep 2020
13F
Palo Alto Investors LP
13F
Company
22%
5,086,152
$74,258,000 30 Sep 2020
13F
STATE STREET CORP
13F
Company
21%
4,788,974
$69,919,000 30 Sep 2020
13F
FRONTIER CAPITAL MANAGEMENT CO LLC
13F
Company
16%
3,703,786
$54,075,000 30 Sep 2020
13F
VANGUARD GROUP INC
13F
Company
15%
3,444,065
$50,284,000 30 Sep 2020
13F
ADAGE CAPITAL PARTNERS GP, L.L.C.
13F
Company
14%
3,212,931
$46,909,000 30 Sep 2020
13F
D. E. Shaw & Co., Inc.
13F
Company
11%
2,387,470
$34,857,000 30 Sep 2020
13F
ALKEON CAPITAL MANAGEMENT LLC
13F
Company
9.6%
2,164,900
$31,608,000 30 Sep 2020
13F
WELLINGTON MANAGEMENT GROUP LLP
13F
Company
7.7%
1,742,700
$25,443,000 30 Sep 2020
13F
EMERALD ADVISERS, LLC
13F
Company
7.1%
1,603,253
$23,407,000 30 Sep 2020
13F
RICE HALL JAMES & ASSOCIATES, LLC
13F
Company
6.4%
1,455,222
$21,246,000 30 Sep 2020
13F
EMERALD MUTUAL FUND ADVISERS TRUST
13F
Company
6.4%
1,449,517
$21,163,000 30 Sep 2020
13F
PRICE T ROWE ASSOCIATES INC /MD/
13F
Company
6.3%
1,437,011
$20,980,000 30 Sep 2020
13F
TWO SIGMA INVESTMENTS, LP
13F
Company
5.7%
1,287,652
$18,800,000 30 Sep 2020
13F
TWO SIGMA ADVISERS, LP
13F
Company
5.2%
1,185,900
$17,314,000 30 Sep 2020
13F
GEODE CAPITAL MANAGEMENT, LLC
13F
Company
4.7%
1,055,335
$15,407,000 30 Sep 2020
13F
Nuveen Asset Management, LLC
13F
Company
4.6%
1,052,236
$15,363,000 30 Sep 2020
13F
CITADEL ADVISORS LLC
13F
Company
4.1%
927,438
$13,541,000 30 Sep 2020
13F
Hood River Capital Management LLC
13F
Company
4%
915,760
$13,370,000 30 Sep 2020
13F
GOLDMAN SACHS GROUP INC
13F
Company
3.8%
864,678
$12,624,000 30 Sep 2020
13F
NORTHERN TRUST CORP
13F
Company
3.8%
851,707
$12,435,000 30 Sep 2020
13F
Fairmount Funds Management LLC
13F
Company
3.1%
702,351
$10,254,000 30 Sep 2020
13F
DIMENSIONAL FUND ADVISORS LP
13F
Company
3.1%
697,608
$10,185,000 30 Sep 2020
13F
AMI ASSET MANAGEMENT CORP
13F
Company
2.7%
612,962
$8,949,000 30 Sep 2020
13F
S.c.a. Candriam
13F
Individual
2.3%
523,370
$7,641,000 30 Sep 2020
13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC
13F
Company
2.3%
515,909
$7,533,000 30 Sep 2020
13F
MORGAN STANLEY
13F
Company
1.9%
435,578
$6,359,000 30 Sep 2020
13F
MACQUARIE GROUP LTD
13F
Company
1.7%
381,332
$5,567,000 30 Sep 2020
13F
Point72 Asset Management, L.P.
13F
Company
1.5%
349,723
$5,106,000 30 Sep 2020
13F
Bank of New York Mellon Corp
13F
Company
1.5%
346,513
$5,059,000 30 Sep 2020
13F
JPMORGAN CHASE & CO
13F
Company
1.4%
318,985
$4,653,000 30 Sep 2020
13F
Granahan Investment Management, LLC
13F
Company
1.2%
267,697
$3,908,000 30 Sep 2020
13F
SUSQUEHANNA INTERNATIONAL GROUP, LLP
13F
Company
1%
230,889
$3,371,000 30 Sep 2020
13F
CREDIT SUISSE AG/
13F
Company
1%
226,435
$3,306,000 30 Sep 2020
13F
UBS Group AG
13F
Company
0.9%
203,619
$2,973,000 30 Sep 2020
13F
Allianz Asset Management GmbH
13F
Company
0.86%
194,817
$2,844,000 30 Sep 2020
13F
J. Goldman & Co LP
13F
Company
0.8%
181,904
$2,656,000 30 Sep 2020
13F
BANK OF AMERICA CORP /DE/
13F
Company
0.79%
179,818
$2,625,000 30 Sep 2020
13F
WELLS FARGO & COMPANY/MN
13F
Company
0.79%
179,008
$2,614,000 30 Sep 2020
13F
FMR LLC
13F
Company
0.78%
177,010
$2,584,000 30 Sep 2020
13F
Integral Health Asset Management, LLC
13F
Company
0.77%
175,000
$2,555,000 30 Sep 2020
13F
Phocas Financial Corp.
13F
Company
0.75%
169,525
$2,475,000 30 Sep 2020
13F
Birchview Capital, LP
13F
Company
0.74%
168,000
$2,453,000 30 Sep 2020
13F
MILLENNIUM MANAGEMENT LLC
13F
Company
0.73%
164,973
$2,409,000 30 Sep 2020
13F
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM
13F
Company
0.7%
159,227
$2,325,000 30 Sep 2020
13F
Squarepoint Ops LLC
13F
Company
0.7%
158,523
$2,314,000 30 Sep 2020
13F
Laurion Capital Management LP
13F
Company
0.66%
149,752
$2,186,000 30 Sep 2020
13F
Rafferty Asset Management, LLC
13F
Company
0.62%
139,729
$2,040,000 30 Sep 2020
13F
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC
13F
Company
0.61%
138,176
$2,017,000 30 Sep 2020
13F

Institutional Holders of Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI) as of Q4 2020

As of 31 Dec 2020, Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI) was held by 165 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 63,829,194 shares. The largest 10 holders included BlackRock Inc., STATE STREET CORP, Palo Alto Investors LP, VANGUARD GROUP INC, FRONTIER CAPITAL MANAGEMENT CO LLC, ALKEON CAPITAL MANAGEMENT LLC, MILLENNIUM MANAGEMENT LLC, ADAGE CAPITAL PARTNERS GP, L.L.C., Delphi Management Partners VIII, L.L.C., and WELLINGTON MANAGEMENT GROUP LLP. This page lists 165 institutional shareholders reporting positions in this security for the Q4 2020 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period

Compare Q4 2020 vs Q3 2020 Across Filers

Q3 2020 holders
155
Q4 2020 holders
165
Holder diff
10
Investor Q3 2020 Shares Q4 2020 Shares Share Diff Share Chg % Q3 2020 Value $ Q4 2020 Value $ Value Diff $ Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
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