Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI)

Q: What does CUSIP 48576U106 represent in this 13F holders report?

CUSIP 48576U106 is the security identifier for KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share used to aggregate holder disclosures.

Q: How many institutions held KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share in Q3 2019?

105 institutional investors reported KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share for Q3 2019. Use the holders table for investor-level position and value details.

CUSIP: 48576U106

Q3 2019 13F Holders as of 30 Sep 2019

Security type / class: Equity / Common Stock, par value $0.0001 per share
Total 13F shares: 58,481,490
Total 13F value: $562,607,545
Share change: +7,315,198
Put/Call ratio: 98%
SEC-reported price per share: $9.62
Number of holders: 105
Value change: +$83,519,427
Number of buys: 63
Number of sells: 45
Shares outstanding: 22,658,403

Security key

48576U106

Report period

Q3 2019

Institutions

105

Top holders

KPTI full security history Ownership snapshot Full 13F holder table Newer quarter: Q3 2025 Karyopharm Therapeutics Inc. SEC filings Karyopharm Therapeutics Inc. company facts

Broader feeds

Latest 13F filings Latest 13D/G filings Investors directory

Reporting periods

Holder history for CUSIP 48576U106

Newer quarter: Q3 2025

Recent filing periods:

Q1 2026 Q4 2025 Q3 2025

Ownership snapshot

Top reported holders of KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader

WELLINGTON MANAGEMENT GRO...

Disclosed value leader

WELLINGTON MANAGEMENT GRO...

Comparable rows

15/15

Latest evidence

30 Jun 2019

13F Lead comparable stake: 37% Showing 1-6 of 15 holder rows.

Quick read

WELLINGTON MANAGEMENT GROUP LLP leads the comparable SEC ownership view at 37%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens WELLINGTON MANAGEMENT GROUP LLP's linked filing trail.

Comparable ownership Top 5

WELLINGTON MANAGEMENT GROUP LLP 37%

Consonance Capital Management LP 26%

Palo Alto Investors LP 23%

BlackRock Finance, Inc. 20%

ORBIMED ADVISORS LLC 14%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows

Holder	Evidence	Ownership %	Position	12M Net Δ	As of
WELLINGTON MANAGEMENT GROUP LLP	13F Company 13F	37%	$50,547,000 8,438,412 shares	—	30 Jun 2019
Consonance Capital Management LP	13F Company 13F	26%	$34,761,000 5,803,227 shares	—	30 Jun 2019
Palo Alto Investors LP	13F Company 13F	23%	$31,521,000 5,262,263 shares	—	30 Jun 2019
BlackRock Finance, Inc.	13F Company 13F	20%	$27,112,000 4,526,508 shares	—	30 Jun 2019
ORBIMED ADVISORS LLC	13F Company 13F	14%	$18,859,000 3,148,475 shares	—	30 Jun 2019
VANGUARD GROUP INC	13F Company 13F	13%	$17,874,000 2,983,862 shares	—	30 Jun 2019

How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q3 2019

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions

105

58,481,490

Rows available

105

Investor	Option	Weight %	Change %	SEC-reported value	* Price	Shares	Share Change	Activity	Report Period

^* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q3 2019 vs Q4 2025 Across Filers

Q4 2025 holders

Q3 2019 holders

105

Holder diff

105

Investor	Q4 2025 Shares	Q3 2019 Shares	Share Diff	Share Chg %	Q4 2025 value	Q3 2019 value	Value change	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend